Jo Wu

The IMPACT-CKM scoping review protocol aims to map and synthesize global evidence on predictors, mechanisms, and major adverse cardiovascular events (MACE) associated with Cardiovascular–Kidney–Metabolic (CKM) syndrome. The review will use a structured search of biomedical databases to identify studies related to metabolic syndrome, chronic kidney disease, diabetes mellitus, hypertension, and related conditions. It will characterize key risk factors, disease progression patterns, and clinical and social determinants influencing adverse cardiovascular outcomes. The findings will highlight evidence gaps and inform future research, risk stratification, and integrated CKM care strategies.

This registration contains the protocol for a scoping review titled “Interactive AI for Patients with Cardiovascular Disease and Comorbidities.” The review aims to map the existing literature on the feasibility and acceptability of AI-guided mindfulness and relaxation interventions for individuals with cardiovascular disease and comorbidities. It will examine the types of AI-based interventions used, user acceptance, usability, and ease of use across different modalities, including interactive, embodied, and video-based systems. The review will also summarize reported outcomes related to emotional wellbeing, such as anxiety, mood, and psychological distress. This registration outlines the eligibility criteria, search strategy, study selection process, and data charting methods in accordance with scoping review methodology.

This scoping review will be conducted according to the recommendation of the JBI methodology for scoping review (Peters et al., 2020). The reporting of this scoping review will be guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) (Tricco et al., 2018).

This scoping review will consider quantitative, qualitative or mixed methods study design, as well as systematic reviews, integrative reviews, and other forms of research synthesis for inclusion. Text and opinion papers such as editorial columns, as well as study protocols will be considered for inclusion in the proposed scoping review, if they meet inclusion criteria.

Objective: This rapid review aims to evaluate qualitative literature on the health system enablers and barriers to continuity of care for Aboriginal and Torres Strait Islander people in Australia and comparable Indigenous populations and countries (i.e., Māori people of New Zealand and First Nations people of Canada) (collectively referred to as First Nations people).

Introduction: The First Nations people of Australia, New Zealand, and Canada experience lower life expectancy than their non-Indigenous counterparts, with chronic conditions contributing to approximately 70% of this disparity. Reduced access to health services and poorer care outcomes attributed to chronic diseases account for a significant proportion of this gap. The sub-optimal management of ongoing care when living with chronic conditions contributes to health disparities in these countries. The South Australian Aboriginal Chronic Disease Consortium identified a critical need to create a protocol, evidence-informed on continuity of care for Aboriginal and Torres Strait Islander people hospitalised for chronic disease. Reduced access to health services contributes to delayed detection of risk factors and disease, limited ongoing disease management, increased risk of potentially preventable hospitalisation, and complex care needs, often unmet following a hospitalisation. An investigation of qualitative literature on system enablers and barriers to continuity of care for First Nations populations with shared histories of colonisation will help inform evidence-based approaches to continuity of care.

Inclusion criteria: This review will be focused on the qualitative and mixed-method studies that qualify enablers and barriers to continuity of care. It will consider frameworks, protocols, and designs concerning specific chronic conditions, which are the major contributors to health disparities, and the focus of the South Australian Aboriginal Chronic Disease Consortium: cancer, cardiovascular disease, chronic kidney disease, and diabetes and its associated complications. An emphasis will be placed on the health system, healthcare providers, and other professionals related to continuity of care services or integration of care.

Exclusion criteria: The work will exclude research that does not consider enablers and/or barriers to continuity of care or its integration. Quantitative studies and those considering chronic conditions outside this scope will be excluded.

Methods: This rapid qualitative review will consider relevant primary qualitative and mixed-methods studies published in English between 2010 and June 2022. Key information sources to be searched for publications will be databases Medline, Embase, PsycINFO, and Cochrane Central. Two reviewers will independently review titles and abstracts; relevant sources will be retrieved in full and reviewed. Any disagreements will be resolved through discussion or with one or more additional reviewers. Two independent reviewers will assess papers selected for retrieval for methodological quality using the Aboriginal and Torres Strait Islander quality appraisal tool before inclusion in the review. Relevant articles will be charted to summarise the extracted data. Findings will be explained inductively, in narrative and graphical forms, using the latest frameworks from The World Health Organisation as a lens but allowing themes to emerge from the data. Any deviations from this protocol will be justified and reported in the final review.