Associations of components of sarcopenic obesity with bone health and balance in older adults

David Scott; Catherine Shore-Lorenti; Lachlan McMillan; Jakub Mesinovic; Ross Clark; Alan Hayes; Kerrie M Sanders; Gustavo Duque; Peter R Ebeling

doi:10.1016/j.archger.2017.12.006

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Associations of components of sarcopenic obesity with bone health and balance in older adults

Journal article

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Peer reviewed

Associations of components of sarcopenic obesity with bone health and balance in older adults

David Scott, Catherine Shore-Lorenti, Lachlan McMillan, Jakub Mesinovic, Ross Clark, Alan Hayes, Kerrie M Sanders, Gustavo Duque and Peter R Ebeling

Archives of Gerontology and Geriatrics, Vol.75, pp.125-131

2018

DOI: https://doi.org/10.1016/j.archger.2017.12.006

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Abstract

sarcopenic obesity

muscle density

bone

osteoporosis

balance

muscle strength

Objectives: To determine characteristics of sarcopenic obesity that are independently associated with bone health and balance in older adults. Study design: Cross-sectional study of 168 community-dwelling older adults (mean age 67.7±8.4 years; 55% women). Main outcome measures: Appendicular lean mass (ALM), whole-body areal BMD (aBMD) and body fat percentage were assessed by dual-energy X-ray absorptiometry. Peripheral quantitative computed tomography assessed muscle density and cortical volumetric BMD (vBMD), area, thickness, and strength-strain index (SSI) at 66% tibial length. Hand grip strength (dynamometry) and balance path length (computerised posturography) were assessed. Obesity was defined as high body fat percentage. Results: Greater lower-leg muscle density was associated with lower balance path length in men (r=-0.36; P<0.01) and women (r=-0.40; P=<0.01). Obese participants by body fat percentage did not differ to non-obese on bone indices, although a trend towards lower cortical vBMD was observed in obese compared with non-obese men (1041.4±39.8 vs 1058.8±36.1 mg/cm3; P=0.051). In multivariable models, ALM was positively associated with all bone parameters in obese women, and with whole-body aBMD, proximal tibial cortical area and SSI in non-obese women, and both non-obese and obese men (all P<0.05). Lower-leg muscle density was also positively associated with cortical vBMD (B=2.91; 95% CI 0.02, 5.80) and area (2.70; 0.06, 5.33) in obese women. Conclusions: Amongst components of sarcopenic obesity, higher ALM is a consistent independent predictor of better bone health. Low muscle density may also compromise bone health and balance. Interventions which improve muscle mass and composition may lower fracture risk in sarcopenic obesity.

Details

Title: Associations of components of sarcopenic obesity with bone health and balance in older adults
Authors: David Scott (Author) - Monash University
Catherine Shore-Lorenti (Author) - Monash University
Lachlan McMillan (Author) - Monash University
Jakub Mesinovic (Author) - Monash University
Ross Clark (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and Engineering
Alan Hayes (Author) - University of Melbourne
Kerrie M Sanders (Author) - University of Melbourne
Gustavo Duque (Author) - University of Melbourne
Peter R Ebeling (Author) - Monash University
Publication details: Archives of Gerontology and Geriatrics, Vol.75, pp.125-131
Publisher: Elsevier Ireland Ltd.
Date published: 2018
DOI: 10.1016/j.archger.2017.12.006
ISSN: 0167-4943
Copyright note: Copyright © 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Organisation Unit: University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy; School of Health and Behavioural Sciences - Legacy; School of Health - Public Health
Language: English
Record Identifier: 99451261602621
Output Type: Journal article