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Preprint
Atypical cortical encoding of speech identifies children with Dyslexia versus Developmental Language Disorder
bioRxiv, Vol.27 October 2022
Cold Spring Harbor Laboratory Press
2022
Abstract
Slow cortical oscillations play a crucial role in processing the speech envelope, which is perceived atypically by children with Developmental Language Disorder (DLD) and developmental dyslexia. Here we use electroencephalography (EEG) and natural speech listening paradigms to identify neural processing patterns that characterize dyslexic versus DLD children. Using a story listening paradigm, we show that atypical power dynamics and phase-amplitude coupling between delta and theta oscillations characterize dyslexic and DLD children groups, respectively. We further identify EEG common spatial patterns (CSP) during speech listening across delta, theta and beta oscillations describing dyslexic versus DLD children. A linear classifier using four deltaband CSP variables predicted dyslexia status (0.77 AUC). Crucially, these spatial patterns also identified children with dyslexia in a rhythmic syllable task EEG, suggesting a core developmental deficit in neural processing of speech rhythm. These findings suggest that there are distinct atypical neurocognitive mechanisms underlying dyslexia and DLD.
Details
- Title
- Atypical cortical encoding of speech identifies children with Dyslexia versus Developmental Language Disorder
- Authors
- João Araújo (Corresponding Author) - University of CambridgeBenjamin D Simons (Author) - University of CambridgeVarghese Peter (Author) - University of the Sunshine Coast, Queensland, School of Health and Behavioural Sciences - LegacyKanad Mandke (Author) - University of CambridgeMarina Kalashnikova (Author) - Basque Center on Cognition, Brain and LanguageAnnabel Macfarlane (Author) - University of CambridgeFiona Gabrielczyk (Author) - University of CambridgeAngela Wilson (Author) - University of CambridgeGiovanni M Di Liberto (Author) - Trinity College DublinDenis Burnham (Author) - Western Sydney UniversityUsha Goswami (Author) - University of Cambridge
- Publication details
- bioRxiv, Vol.27 October 2022
- Publisher
- Cold Spring Harbor Laboratory Press
- Date published
- 2022
- DOI
- 10.1101/2022.10.26.513864
- ISSN
- 2692-8205
- Copyright note
- The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
- Organisation Unit
- University of the Sunshine Coast, Queensland; School of Health - Psychology; School of Health and Behavioural Sciences - Legacy
- Language
- English
- Record Identifier
- 99684998802621
- Output Type
- Preprint
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