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Published VersionCC BY V4.0, Open Access
Journal article
Wide-field choroidal thickness in myopes and emmetropes
Scientific Reports, Vol.9, pp.1-10
2019
PMCID: PMC6401121
PMID: 30837507
Abstract
There is a paucity of knowledge regarding the normal in-vivo thickness of the choroid beyond the macula (similar to 17 degrees). In this study, the choroidal thickness of 27 healthy young adults was examined across the macular (the central 5 mm including the fovea, parafovea, and perifovea) and extra-macular (a 5-14 mm annulus including the near-periphery and periphery) regions using wide-field optical coherence tomography, and compared between emmetropes (n = 14) and myopes (n = 13). The choroid progressively thinned beyond the parafovea (350 +/- 86 mu m) towards the periphery (264 +/- 44 mu m), and was thickest superiorly (355 +/- 76 mu m) and thinnest nasally (290 +/- 79 mu m). Choroidal thickness also varied with refractive error; myopes exhibited a thinner choroid than emmetropes in the macular region (311 +/- 88 vs. 383 +/- 66 mu m), however, this difference diminished towards the periphery (251 +/- 48 vs. 277 +/- 37 mu m). Meridional variations in choroidal thickness were not different between myopes and emmetropes. In conclusion, the choroid was thickest within the perifovea; thinned substantially towards the periphery, and exhibited the minimum and maximum peripheral thinning superiorly and nasally across a 55 degrees region respectively. Choroidal thinning associated with myopia was more pronounced in the macular than extra-macular regions.
Details
- Title
- Wide-field choroidal thickness in myopes and emmetropes
- Authors
- Hosein Hoseini-Yazdi (Corresponding Author) - Queensland University of TechnologyStephen J. Vincent (Author) - Queensland University of TechnologyMichael J. Collins (Author) - Queensland University of TechnologyScott A. Read (Author) - Queensland University of TechnologyDavid Alonso-Caneiro (Author) - Queensland University of Technology
- Publication details
- Scientific Reports, Vol.9, pp.1-10
- Publisher
- Nature Publishing Group
- Date published
- 2019
- DOI
- 10.1038/s41598-019-39653-w
- ISSN
- 2045-2322
- PMID
- 30837507; PMC6401121
- Copyright note
- © The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
- Data Availability
- The datasets generated and analysed during this study are available from the corresponding author on reasonable request.
- Organisation Unit
- School of Science, Technology and Engineering
- Language
- English
- Record Identifier
- 99973593902621
- Output Type
- Journal article
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