Abstract
Purpose:
To compare measurements of retinal thickness (RT) and choroidal thickness (ChT) obtained with an optical low coherence reflectometry (OLCR) biometer (Lenstar LS 900) with those obtained with a spectral domain optical coherence tomographer (SD OCT) (Copernicus SOCT HR) in young normal subjects.
Methods:
Twenty young adult subjects had foveal RT and subfoveal ChT measurements obtained with OLCR biometry and SD OCT. RT and ChT was derived through manual analysis of A-scan data from the OLCR biometer. An average SD OCT foveal B-scan image derived from a series of 50 multiple B-scans was also analyzed to determine RT and ChT for each subject. Measurements from the two instruments were compared using Pearson correlation and Bland-Altman analysis.
Results:
RT and ChT measurements from the two instruments were highly correlated (r(2) of 0.80 and 0.94, respectively, p < 0.0001). The mean RT with SD OCT and OLCR were 195 +/- 17 mu m and 196 +/- 16 mu m, respectively (mean difference, 1 +/- 8 mu m). The mean ChT was 324 +/- 71 mu m and 328 +/- 84 mu m with SD OCT and OLCR, respectively (mean difference, 4 +/- 24 mu m).
Conclusions:
Foveal RT and subfoveal ChT measures from OLCR biometry exhibit a strong correlation and good agreement with measures derived from SD OCT in a population of young adult subjects.