Using quantitative polymerase chain reaction to correlate Chlamydia pecorum infectious load with ocular, urinary and reproductive tract disease in the koala (Phascolarctos cinereus)

C Wan; J Loader; Jon Hanger; K W Beagley; Peter Timms; Adam Polkinghorne

doi:10.1111/j.1751-0813.2011.00827.x

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Using quantitative polymerase chain reaction to correlate Chlamydia pecorum infectious load with ocular, urinary and reproductive tract disease in the koala (Phascolarctos cinereus)

Journal article

Peer reviewed

Using quantitative polymerase chain reaction to correlate Chlamydia pecorum infectious load with ocular, urinary and reproductive tract disease in the koala (Phascolarctos cinereus)

C Wan, J Loader, Jon Hanger, K W Beagley, Peter Timms and Adam Polkinghorne

Australian Veterinary Journal, Vol.89(10), pp.409-412

2011

DOI: https://doi.org/10.1111/j.1751-0813.2011.00827.x

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Abstract

Chlamydia

conjunctivitis

cystitis

koalas

infertility

quantitative polymerase chain reaction

Complex interactions between Chlamydia pecorum infection, the immune response and disease exist in the koala. We used quantitative polymerase chain reaction to investigate the relationship between C. pecorum infectious load and ocular and urogenital tract disease. Chlamydia pecorum shedding was generally higher in animals with chronic, active disease than in animals with inactive disease. The absence of ocular disease was generally associated with low levels of shedding, but relatively high levels of shedding in the urogenital tract were detected in some koalas without clinical disease signs. These results suggest a complex disease pathogenesis and clinical course in C. pecorum-infected koalas.

Details

Title: Using quantitative polymerase chain reaction to correlate Chlamydia pecorum infectious load with ocular, urinary and reproductive tract disease in the koala (Phascolarctos cinereus)
Authors: C Wan (Author) - Queensland University of Technology
J Loader (Author) - Australian Wildlife Hospital - Australia Zoo
Jon Hanger (Author) - Australian Wildlife Hospital - Australia Zoo
K W Beagley (Author) - Queensland University of Technology
Peter Timms (Author) - Queensland University of Technology
Adam Polkinghorne (Author) - Queensland University of Technology
Publication details: Australian Veterinary Journal, Vol.89(10), pp.409-412
Publisher: Wiley-Blackwell Publishing Ltd.
Date published: 2011
DOI: 10.1111/j.1751-0813.2011.00827.x
ISSN: 0005-0423; 0005-0423
Organisation Unit: University of the Sunshine Coast, Queensland; Centre for Bioinnovation
Language: English
Record Identifier: 99449052902621
Output Type: Journal article

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