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Published VersionCC BY V4.0, Open Access
Journal article
Use of focus measure operators for characterization of flood illumination adaptive optics ophthalmoscopy image quality
Biomedical Optics Express, Vol.9(2), pp.679-693
2018
PMCID: PMC5854070
PMID: 29552404
Abstract
Adaptive optics flood illumination ophthalmoscopy (AO-FIO) allows imaging of the cone photoreceptor in the living human retina. However, clinical interpretation of the AO-FIO image remains challenging due to suboptimal quality arising from residual uncorrected wavefront aberrations and rapid eye motion. An objective method of assessing image quality is necessary to determine whether an AO-FIO image is suitable for grading and diagnostic purpose. In this work, we explore the use of focus measure operators as a surrogate measure of AO-FIO image quality. A set of operators are tested on data sets acquired at different focal depths and different retinal locations from healthy volunteers. Our results demonstrate differences in focus measure operator performance in quantifying AO-FIO image quality. Further, we discuss the potential application of the selected focus operators in (i) selection of the best quality AO-FIO image from a series of images collected at the same retinal location and (ii) assessment of longitudinal changes in the diseased retina. Focus function could be incorporated into real-time AO-FIO image processing and provide an initial automated quality assessment during image acquisition or reading center grading.
Details
- Title
- Use of focus measure operators for characterization of flood illumination adaptive optics ophthalmoscopy image quality
- Authors
- David Alonso-Caneiro (Corresponding Author) - Queensland University of TechnologyDanuta M. Sampson (Author) - The University of Western AustraliaAvenell L. Chew (Author) - The University of Western AustraliaMichael J. Collins (Author) - Queensland University of TechnologyFred K. Chen (Author) - The University of Western Australia
- Publication details
- Biomedical Optics Express, Vol.9(2), pp.679-693
- Publisher
- Optica
- Date published
- 2018
- DOI
- 10.1364/BOE.9.000679
- ISSN
- 2156-7085
- PMID
- 29552404; PMC5854070
- Copyright note
- © 2018 Optical Society of America. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reserved.
- Grant note
- Ophthalmic Research Institute of Australia Bayer Global Ophthalmology Awards Program Telethon - Perth Children's Hospital Research Fund APPI142962 / National Health and Medical Research Council; National Health and Medical Research Council (NHMRC) of Australia
- Organisation Unit
- School of Science, Technology and Engineering
- Language
- English
- Record Identifier
- 99973597902621
- Output Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web Of Science research areas
- Biochemical Research Methods
- Optics
- Radiology, Nuclear Medicine & Medical Imaging
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Source: InCites