Understanding the evidence for medical cannabis and cannabis-based medicines for the treatment of chronic non-cancer pain

Gabrielle Campbell; Emily Stockings; Suzanne Nielsen

doi:10.1007/s00406-018-0960-9

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Understanding the evidence for medical cannabis and cannabis-based medicines for the treatment of chronic non-cancer pain

Journal article

Peer reviewed

Understanding the evidence for medical cannabis and cannabis-based medicines for the treatment of chronic non-cancer pain

Gabrielle Campbell, Emily Stockings and Suzanne Nielsen

European Archives of Psychiatry and Clinical Neuroscience, Vol.269, pp.135-144

2019

DOI: https://doi.org/10.1007/s00406-018-0960-9

PMID: 30635715

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Abstract

Neurosciences

Cannabis

Medicine & Public Health

Cannabis-based medicines

Psychiatry

Chronic pain

Medical cannabis

The use of medical cannabis and cannabis-based medicines has received increasing interest in recent years; with a corresponding surge in the number of studies and reviews conducted in the field. Despite this growth in evidence, the findings and conclusions of these studies have been inconsistent. In this paper, we outline the current evidence for medical cannabis and cannabis-based medicines in the treatment and management of chronic non-cancer pain. We discuss limitations of the current evidence, including limitations of randomised control trials in the field, limits on generalisability of previous findings and common issues such as problems with measurements of dose and type of cannabinoids. We discuss future directions for medicinal cannabinoid research, including addressing limitations in trial design; developing frameworks to monitor for use disorder and other unintended outcomes; and considering endpoints other than 30% or 50% reductions in pain severity.

Details

Title: Understanding the evidence for medical cannabis and cannabis-based medicines for the treatment of chronic non-cancer pain
Authors: Gabrielle Campbell (Corresponding Author) - UNSW Australia
Emily Stockings (Author) - UNSW Australia
Suzanne Nielsen (Author) - Monash University
Publication details: European Archives of Psychiatry and Clinical Neuroscience, Vol.269, pp.135-144
Publisher: Springer Medizin
Date published: 2019
DOI: 10.1007/s00406-018-0960-9
ISSN: 1433-8491
PMID: 30635715
Organisation Unit: University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy; School of Health and Behavioural Sciences - Legacy
Language: English
Record Identifier: 99472501002621
Output Type: Journal article

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Collaboration types: Domestic collaboration
Web Of Science research areas: Clinical Neurology; Psychiatry

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