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Ultrastructural study of Chlamydia pneumoniae in a continuous-infection model
Journal article   Open access   Peer reviewed

Ultrastructural study of Chlamydia pneumoniae in a continuous-infection model

A Kutlin, C Flegg, D Stenzel, T Reznik, P M Roblin, S Mathews, Peter Timms and M R Hammerschlag
Journal of Clinical Microbiology, Vol.39(10), pp.3721-3723
2001
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https://doi.org/10.1128/JCM.39.10.3721-3723.2001View
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Abstract

We have established an in vitro model of long-term continuous Chlamydia pneumoniae infection in HEp-2 cells. Using transmission electron microscopy, we demonstrated the presence of spontaneous abnormal chlamydial inclusions similar in appearance to the persistent chlamydial forms induced in vitro by treatment with cytokines or antibiotics or by nutrient deprivation.

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