Type and Frequency in Use of Nutraceutical and Micronutrient Supplementation for the Management of Polycystic Ovary Syndrome: A Systematic Scoping Review

Nicole Scannell; Evangeline Mantzioris; Vibhuti Rao; Chhiti Pandey; Carolyn Ee; Aya Mousa; Lisa Moran; Anthony Villani

doi:10.3390/biomedicines11123349

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Type and Frequency in Use of Nutraceutical and Micronutrient Supplementation for the Management of Polycystic Ovary Syndrome: A Systematic Scoping Review

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Type and Frequency in Use of Nutraceutical and Micronutrient Supplementation for the Management of Polycystic Ovary Syndrome: A Systematic Scoping Review

Nicole Scannell, Evangeline Mantzioris, Vibhuti Rao, Chhiti Pandey, Carolyn Ee, Aya Mousa, Lisa Moran and Anthony Villani

Biomedicines, Vol.11(12), pp.1-16

2023

DOI: https://doi.org/10.3390/biomedicines11123349

PMCID: PMC10742329

PMID: 38137570

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Abstract

supplements

micronutrients

pcos

nutraceuticals

polycystic ovary syndrome

Lifestyle strategies are considered first-line treatment for the management of polycystic ovary syndrome (PCOS). However, complementary therapies, including nutrient supplementation, have been identified as a potential adjunct therapy. Therefore, we systematically mapped the available literature to identify the type and frequency of the use of nutraceutical and micronutrient supplementation for the management of PCOS features. A systematic search of the literature was conducted using CINAHL, Cochrane reviews, Medline, PsycINFO, Scopus and LILACS. All types of study designs were included if they reported on the use of nutraceuticals and/or micronutrient supplementation on features of PCOS in women aged ≥18 years. A total of 344 articles were included. Forty-one supplements were identified, with the most frequently investigated being inositols (n = 86), vitamin D (n = 53), N-acetylcysteine (n = 27) and omega-3 fatty acids (n = 25). Reproductive outcomes were the most commonly reported (n = 285; 83%), followed by metabolic (n = 229; 67%), anthropometric (n = 197; 57%) and psychological (n = 8; 2%). Our results identified that nutraceutical and micronutrient supplementation require further investigation of psychological outcomes in women with PCOS. Moreover, adequately powered primary studies are warranted to investigate therapeutic doses needed for clinical benefits.

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Title: Type and Frequency in Use of Nutraceutical and Micronutrient Supplementation for the Management of Polycystic Ovary Syndrome: A Systematic Scoping Review
Authors: Nicole Scannell (Author) - University of the Sunshine Coast, Queensland, School of Health - Midwifery
Evangeline Mantzioris (Author) - University of South Australia
Vibhuti Rao (Author) - Western Sydney University
Chhiti Pandey (Author) - Monash University
Carolyn Ee (Author) - Western Sydney University
Aya Mousa (Author) - Monash University
Lisa Moran (Author) - Monash University
Anthony Villani (Corresponding Author) - University of the Sunshine Coast, Queensland, School of Health - Nutrition & Dietetics
Publication details: Biomedicines, Vol.11(12), pp.1-16
Publisher: MDPI AG
Date published: 2023
DOI: 10.3390/biomedicines11123349
ISSN: 2227-9059
PMID: 38137570; PMC10742329
Copyright note: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Data Availability: The datasets generated during and/or analysed during this scoping review are available from the corresponding author upon reasonable request.
Organisation Unit: Graduate Research School; School of Health - Nutrition & Dietetics; School of Health and Sport Sciences - Legacy; School of Health - Midwifery
Language: English
Record Identifier: 99984360202621
Output Type: Journal article

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