Journal article
Transitions Study of Predictors of illness progression in young people with mental ill Health: Study methodology
Early Intervention in Psychiatry, Vol.9(1), pp.38-47
2015
Abstract
Aim: An estimated 75% of mental disorders begin before the age of 24 and approximately 25% of 13-24-year-olds are affected by mental disorders at any one time. To better understand and ideally prevent the onset of post-pubertal mental disorders, a clinical staging model has been proposed that provides a longitudinal perspective of illness development. This heuristic model takes account of the differential effects of both genetic and environmental risk factors, as well as markers relevant to the stage of illness, course or prognosis. The aim of the Transitions Study is to test empirically the assumptions that underpin the clinical staging model. Additionally, it will permit investigation of a range of psychological, social and genetic markers in terms of their capacity to define current clinical stage or predict transition from less severe or enduring to more severe and persistent stages of mental disorder. Method: This paper describes the study methodology, which involves a longitudinal cohort design implemented within four headspace youth mental health services in Australia. Participants are young people aged 12-25 years who have sought help at headspace and consented to complete a comprehensive assessment of clinical state and psychosocial risk factors. A total of 802 young people (66% female) completed baseline assessments. Annual follow-up assessments have commenced. Conclusions: The results of this study may have implications for the way mental disorders are diagnosed and treated, and progress our understanding of the pathophysiologies of complex mental disorders by identifying genetic or psychosocial markers of illness stage or progression. © 2015 Wiley Publishing Asia Pty Ltd.
Details
- Title
- Transitions Study of Predictors of illness progression in young people with mental ill Health: Study methodology
- Authors
- R Purcell (Author) - University of MelbourneA F Jorm (Author) - University of MelbourneI B Hickie (Author) - University of SydneyA R Yung (Author) - University of MelbourneC Pantelis (Author) - University of MelbourneG P Amminger (Author) - University of MelbourneN Glozier (Author) - University of SydneyE Killackey (Author) - University of MelbourneL Phillips (Author) - University of MelbourneS J Wood (Author) - University of MelbourneA Mackinnon (Author) - University of MelbourneE Scott (Author) - University of SydneyA Kenyon (Author) - University of SydneyL Mundy (Author) - University of MelbourneA Nichles (Author) - University of SydneyA Scaffidi (Author) - University of MelbourneD Spiliotacopoulos (Author) - University of MelbourneL Taylor (Author) - University of MelbourneJ P Y Tong (Author) - University of MelbourneS Wiltink (Author) - University of MelbourneN Zmicerevska (Author) - University of SydneyDaniel F Hermens (Author) - University of SydneyA Guastella (Author) - University of SydneyP D McGorry (Author) - University of Melbourne
- Publication details
- Early Intervention in Psychiatry, Vol.9(1), pp.38-47
- Publisher
- Wiley-Blackwell Publishing Asia
- Date published
- 2015
- DOI
- 10.1111/eip.12079
- ISSN
- 1751-7885
- Organisation Unit
- University of the Sunshine Coast, Queensland; Thompson Institute
- Language
- English
- Record Identifier
- 99451161202621
- Output Type
- Journal article
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- Psychiatry
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