Journal article
The streptococcal M protein: a highly versatile molecule
Trends in Microbiology, Vol.18(6), pp.275-282
2010
Abstract
Interaction of the M-protein of group A Streptococcus (GAS) with its numerous host binding partners might assist the bacteria in evading host immune responses. Although the extensive diversity of this protein has been highlighted by different GAS typing schemes, most of the structural and functional information has been obtained from a limited number of types. Increasing numbers of epidemiological, clinical and biological reports suggest that the structure and function of the M protein is less conserved than previously thought. This review focuses on the known interactions between M proteins and host ligand proteins, emphasizing that our understanding of this well-studied molecule is fragmented.
Details
- Title
- The streptococcal M protein: a highly versatile molecule
- Authors
- P R Smeesters (Author) - Queensland Institute of Medical ResearchDavid J McMillan (Author) - Queensland Institute of Medical ResearchK S Sriprakash (Author) - Queensland Institute of Medical Research
- Publication details
- Trends in Microbiology, Vol.18(6), pp.275-282
- Publisher
- Elsevier Ltd.
- Date published
- 2010
- DOI
- 10.1016/j.tim.2010.02.007
- ISSN
- 0966-842X
- Organisation Unit
- University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy; School of Science, Technology and Engineering; Centre for Bioinnovation
- Language
- English
- Record Identifier
- 99450150502621
- Output Type
- Journal article
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- Microbiology
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