The relative contributions of psychiatric symptoms and psychotropic medications on the sleep-wake profile of young persons with anxiety, depression and bipolar disorders

R Robillard; C Oxley; Daniel F Hermens; D White; R Wallis; S L Naismith; B Whitwell; J Southan; E M Scott; I B Hickie

doi:10.1016/j.psychres.2016.06.025

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The relative contributions of psychiatric symptoms and psychotropic medications on the sleep-wake profile of young persons with anxiety, depression and bipolar disorders

R Robillard, C Oxley, Daniel F Hermens, D White, R Wallis, S L Naismith, B Whitwell, J Southan, E M Scott and I B Hickie

Psychiatry Research, Vol.243, pp.403-406

2016

DOI: https://doi.org/10.1016/j.psychres.2016.06.025

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Abstract

affective disorders

actigraphy

pharmacotherapy

This study investigated the relative contribution of psychiatric symptoms and psychotropic medications on the sleep-wake cycle. Actigraphy and clinical assessments (Brief Psychiatric Rating Scale) were conducted in 146 youths with anxiety, depression or bipolar disorders. Independently of medications, mania symptoms were predictive of lower circadian amplitude and rhythmicity. Independently of diagnosis and symptoms severity: i) antipsychotics were related to longer sleep period and duration, ii) serotonin-norepinephrine reuptake inhibitors to longer sleep period, and iii) agomelatine to earlier sleep onset. Manic symptoms and different subclasses of medications may have independent influences on the sleep-wake cycle of young people with mental disorders. © 2016

Details

Title: The relative contributions of psychiatric symptoms and psychotropic medications on the sleep-wake profile of young persons with anxiety, depression and bipolar disorders
Authors: R Robillard (Author) - University of Sydney
C Oxley (Author) - University of Sydney
Daniel F Hermens (Author) - University of Sydney
D White (Author) - University of Sydney
R Wallis (Author) - University of Sydney
S L Naismith (Author) - University of Sydney
B Whitwell (Author) - University of Sydney
J Southan (Author) - University of Sydney
E M Scott (Author) - University of Sydney
I B Hickie (Author) - University of Sydney
Publication details: Psychiatry Research, Vol.243, pp.403-406
Publisher: Elsevier Ireland Ltd.
Date published: 2016
DOI: 10.1016/j.psychres.2016.06.025
ISSN: 0165-1781
Organisation Unit: University of the Sunshine Coast, Queensland; Thompson Institute
Language: English
Record Identifier: 99451159002621
Output Type: Journal article

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