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The phase-variable allele of the pilus glycosylation gene pglA is not strongly associated with strains of Neisseria gonorrhoeae isolated from patients with disseminated gonococcal infection
Journal article   Open access   Peer reviewed

The phase-variable allele of the pilus glycosylation gene pglA is not strongly associated with strains of Neisseria gonorrhoeae isolated from patients with disseminated gonococcal infection

P M Power, S C Ku, Kerry-Lee Rutter, M J Warren, E A Limnios, J W Tapsall and M P Jennings
Infection and immunity, Vol.75(6), pp.3202-3204
2007
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https://doi.org/10.1128/IAI.01501-06View
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Abstract

Biological Sciences Medical and Health Sciences Agricultural and Veterinary Sciences
The Neisseria gonorrhoeae pglA gene has two alleles, one of which is phase variable. A previous study reported that all disseminated gonococcal infection (DGI) isolates contained the phase-variable allele and proposed a causal link. In the present study of 81 strains no absolute correlation between DGI and the phase-variable pglA allele was observed.

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Immunology
Infectious Diseases

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