The influence of microgravity on cerebral blood flow and electrocortical activity

Timo Klein; Petra Wollseiffen; Marit Sanders; Jurgen Claassen; Heather Carnahan; Vera Abeln; Tobias Vogt; Heiko K Struder; Stefan Schneider

doi:10.1007/s00221-019-05490-6

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The influence of microgravity on cerebral blood flow and electrocortical activity

Journal article

Peer reviewed

The influence of microgravity on cerebral blood flow and electrocortical activity

Timo Klein, Petra Wollseiffen, Marit Sanders, Jurgen Claassen, Heather Carnahan, Vera Abeln, Tobias Vogt, Heiko K Struder and Stefan Schneider

Experimental Brain Research, Vol.237(4), pp.1057-1062

2019

DOI: https://doi.org/10.1007/s00221-019-05490-6

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Abstract

parabolic flight

EEG

transcranial doppler ultrasound

Master of Creative Arts

Changes in gravity conditions have previously been reported to influence brain hemodynamics as well as neuronal activity. This paper attempts to identify a possible link between changes in brain blood flow and neuronal activity during microgravity. Middle cerebral artery flow velocity (MCAv) was measured using Doppler ultrasound. Brain cortical activity (i.e., cortical current density) was measured using electroencephalography. Finger blood pressure was recorded and exported to generate beat-by-beat systolic (SBP), diastolic (DBP) and mean arterial pressure (MAP), heart rate (HR), cardiac output (CO), and cerebrovascular conductance index (CVCi). Seventeen participants were evaluated under normal gravity conditions and microgravity conditions, during 15 bouts of 22-s intervals of weightlessness during a parabolic flight. Although MAP decreased and CO increased, MCAv remained unchanged in the microgravity condition. CVCi as the quotient of MCAv and MAP increased in microgravity. Cortical current density showed a global decrease. Our data support earlier data reporting a decrease in the amplitude of event-related potentials recorded during microgravity. However, the general decrease in neural excitability in microgravity seems not to be dependent on hemodynamic changes.

Details

Title: The influence of microgravity on cerebral blood flow and electrocortical activity
Authors: Timo Klein (Author) - University of the Sunshine Coast - School of Health & Sport Sciences
Petra Wollseiffen (Author) - German Sport University Cologne, Germany
Marit Sanders (Author) - Radboud University, Netherlands
Jurgen Claassen (Author) - Radboud University, Netherlands
Heather Carnahan (Author) - Memorial University of Newfoundland, Canada
Vera Abeln (Author) - German Sport University Cologne, Germany
Tobias Vogt (Author) - German Sport University Cologne, Germany
Heiko K Struder (Author) - German Sport University Cologne, Germany
Stefan Schneider (Author) - University of the Sunshine Coast - School of Health & Sport Sciences
Publication details: Experimental Brain Research, Vol.237(4), pp.1057-1062
Publisher: Springer
Date published: 2019
DOI: 10.1007/s00221-019-05490-6
ISSN: 0014-4819
Organisation Unit: University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy
Language: English
Record Identifier: 99451002902621
Output Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Neurosciences

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