Journal article
The influence of high-intensity compared with moderate-intensity exercise training on cardiorespiratory fitness and body composition in colorectal cancer survivors: a randomised controlled trial
Journal of Cancer Survivorship, Vol.10(3), pp.467-479
2016
PMID: 26482384
Abstract
Following colorectal cancer diagnosis and anti-cancer therapy, declines in cardiorespiratory fitness and body composition lead to significant increases in morbidity and mortality. There is increasing interest within the field of exercise oncology surrounding potential strategies to remediate these adverse outcomes. This study compared 4 weeks of moderate-intensity exercise (MIE) and high-intensity exercise (HIE) training on peak oxygen consumption (V̇O2peak) and body composition in colorectal cancer survivors.Forty seven post-treatment colorectal cancer survivors (HIE = 27 months post-treatment; MIE = 38 months post-treatment) were randomised to either HIE [85–95 % peak heart rate (HRpeak)] or MIE (70 % HRpeak) in equivalence with current physical activity guidelines and completed 12 training sessions over 4 weeks.HIE was superior to MIE in improving absolute (p = 0.016) and relative (p = 0.021) V̇O2peak. Absolute (+0.28 L.min−1, p < 0.001) and relative (+3.5 ml.kg−1.min−1, p < 0.001) V̇O2 peak were increased in the HIE group but not the MIE group following training. HIE led to significant increases in lean mass (+0.72 kg, p = 0.002) and decreases in fat mass (−0.74 kg, p < 0.001) and fat percentage (−1.0 %, p < 0.001), whereas no changes were observed for the MIE group. There were no severe adverse events.In response to short-term training, HIE is a safe, feasible and efficacious intervention that offers clinically meaningful improvements in cardiorespiratory fitness and body composition for colorectal cancer survivors.HIE appears to offer superior improvements in cardiorespiratory fitness and body composition in comparison to current physical activity recommendations for colorectal cancer survivors and therefore may be an effective clinical utility following treatment.
Details
- Title
- The influence of high-intensity compared with moderate-intensity exercise training on cardiorespiratory fitness and body composition in colorectal cancer survivors: a randomised controlled trial
- Authors
- James Devin (Author) - University of QueenslandAndrew Sax (Author) - University of QueenslandGareth Hughes (Author) - University of QueenslandDavid Jenkins (Author) - University of QueenslandJoanne Aitken (Author) - Griffith UniversitySuzanne Chambers (Author) - Griffith UniversityJeffrey Dunn (Author) - University of QueenslandKate Bolam (Author) - University of QueenslandTina Skinner (Author) - University of Queensland
- Publication details
- Journal of Cancer Survivorship, Vol.10(3), pp.467-479
- Publisher
- Springer New York LLC
- DOI
- 10.1007/s11764-015-0490-7
- ISSN
- 1932-2267
- PMID
- 26482384
- Organisation Unit
- School of Health and Behavioural Sciences - Legacy; School of Health and Sport Sciences - Legacy; University of the Sunshine Coast, Queensland
- Language
- English
- Record Identifier
- 99488706702621
- Output Type
- Journal article
Metrics
18 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- International collaboration
- Web Of Science research areas
- Oncology
- Social Sciences, Biomedical
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites