The impact of chronic stress burden of 520-d isolation and confinement on the physiological response to subsequent acute stress challenge

B Yi; S Matzel; M Feuerecker; M Horl; C Ladinig; V Abeln; A Chouker; Stefan Schneider

doi:10.1016/j.bbr.2014.12.011

Back

The impact of chronic stress burden of 520-d isolation and confinement on the physiological response to subsequent acute stress challenge

Journal article

Peer reviewed

The impact of chronic stress burden of 520-d isolation and confinement on the physiological response to subsequent acute stress challenge

B Yi, S Matzel, M Feuerecker, M Horl, C Ladinig, V Abeln, A Chouker and Stefan Schneider

Behavioural Brain Research, Vol.281, pp.111-115

2015

DOI: https://doi.org/10.1016/j.bbr.2014.12.011

Files and links (1)

url

https://doi.org/10.1016/j.bbr.2014.12.011View

Published Version

Abstract

chronic stress

HPA axis activity

EEG

cortisol

Collective evidence indicates that previous exposure to stressful condition might be able to induce changes in brain structure, HPA axis activity and related neurotransmission, and accordingly affect physiological responses to subsequent challenges. During long-term spaceflight, space travelers have to live under the condition of isolation and confinement in the spacecraft for a long period. It is still largely unknown if this kind of chronic stress burden can induce any long-lasting changes. To address this question, following 520-d isolation and confinement simulating a flight to Mars, the participants and a matched control group were exposed to an acute stress challenge called parabolic flight. Brain cortical activity, HPA axis activity, and sympathetic adrenal-medullary system response were monitored by EEG signal, cortisol secretion, and catecholamine production, respectively. We observed enhanced EEG signals, elevated cortisol levels and increased adrenaline productions. A group effect on cortisol output was revealed showing higher cortisol peak levels in the Mars520 group as compared to the control group, suggesting that HPA axis was to a certain extent more activated in the subjects who had chronic stress experience.

Details

Title: The impact of chronic stress burden of 520-d isolation and confinement on the physiological response to subsequent acute stress challenge
Authors: B Yi (Author) - Hospital of the University of Munich, Germany
S Matzel (Author) - Hospital of the University of Munich, Germany
M Feuerecker (Author) - Hospital of the University of Munich, Germany
M Horl (Author) - Hospital of the University of Munich, Germany
C Ladinig (Author) - Hospital of the University of Munich, Germany
V Abeln (Author) - German Sports Institute of Cologne, Germany
A Chouker (Author) - Hospital of the University of Munich, Germany
Stefan Schneider (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and Engineering
Publication details: Behavioural Brain Research, Vol.281, pp.111-115
Publisher: Elsevier BV
Date published: 2015
DOI: 10.1016/j.bbr.2014.12.011
ISSN: 0166-4328
Organisation Unit: University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy
Language: English
Record Identifier: 99448742902621
Output Type: Journal article

Metrics

20 File views/ downloads

904 Record Views

18 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Behavioral Sciences; Neurosciences

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: InCites