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The effect of anticoagulation on the restoration of range of motion after total knee arthroplasty
Journal article   Peer reviewed

The effect of anticoagulation on the restoration of range of motion after total knee arthroplasty

A C Keays, Marjon Mason, Susan L Keays and P A Newcombe
Journal of Arthroplasty, Vol.18(2), pp.180-185
2003
url
https://doi.org/10.1054/arth.2003.50024View
Published Version

Abstract

Clinical Sciences knee arthroplasty enoxaparin asprin
Anticoagulation used for thromboembolic prophylaxis following total knee arthroplasty (TKA) could interfere with movement. This study compares the effect of 2 anticoagulants, enoxaparin and aspirin, on restoration of range of motion (ROM) after TKA. Two groups of 75 consecutive patients, matched for age, arthritic severity, and preoperative ROM, underwent TKA. Flexion and extension milestone measures were recorded daily. Results show a highly statistically significant difference (P&.001) between the 2 groups when comparing the days on which these milestones were achieved. Group 1 (enoxaparin) reached 90°, 100° and 110° of flexion in 8.4, 10.4, and 12.4 days, respectively. Group 2 (aspirin) reached the same goals in 6.8, 8.5, and 10.6 days, respectively. At 15 months after surgery, no statistically significant difference in flexion was seen between the groups (122° vs 121°). Enoxaparin delayed the return of early but not long-term flexion after TKA.

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