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The Interplay Between Diet and Emerging Allergy: What Can We Learn From Indigenous Australians?
Journal article   Peer reviewed

The Interplay Between Diet and Emerging Allergy: What Can We Learn From Indigenous Australians?

Shelley F Walton and Christopher Weir
International Reviews of Immunology, Vol.31(3), pp.184-201
2012
url
https://doi.org/10.3109/08830185.2012.667180View
Published Version

Abstract

asthma hygiene hypothesis microbiota vitamin A vitamin D
The pathophysiology of atopic diseases, including asthma and allergy, is the result of complex gene-environment interactions. Since European colonization the Indigenous population of Australia has undergone significant changes with respect to their lifestyle as hunter-gatherers. These changes have had a detrimental effect on Aboriginal health, in part due to immunological modification. This review provides a comparative look at both the traditional Aboriginal/Indigenous diet and modern Western diets, examines some common allergies increasingly reported in contemporary Indigenous populations, and reviews concepts such the effect of vitamin deficiencies and changes in gut microbiota on immune function.

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