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Synthesis of ammonium substituted β-cyclodextrins for enantioseparation of anionic analytes
Journal article   Peer reviewed

Synthesis of ammonium substituted β-cyclodextrins for enantioseparation of anionic analytes

I W Muderawan, T T Ong, W H Tang, David James Young, C B Ching and S C Ng
Tetrahedron Letters, Vol.46(10), pp.1747-1749
2005
url
https://doi.org/10.1016/j.tetlet.2005.01.059View
Published Version

Abstract

Organic Chemistry Medicinal and Biomolecular Chemistry cationic cyclodextrins enantiomeric resolution
New ammonium functionalized cyclodextrins can be prepared in excellent yields by displacement of 6-tosyl-β-cyclodextrin with alkylimidazoles, pyridine or alkylamines and achieve excellent enantioseparation of dansyl amino acids presumably due to electrostatic interactions between the cationic host and anionic guest. © 005 Published by Elsevier Ltd.

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Domestic collaboration
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Chemistry, Organic
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