Journal article
Synthesis, crystal structure description, electrochemical and DNA binding studies of ‘paddlewheel’ copper(II) carboxylate
Journal of Coordination Chemistry, Vol.67(10), pp.1731-1745
2014
Abstract
Dimeric paddlewheel copper(II) complex, pyCu(phenylacetate)4Cupy, where py = pyridine, has been prepared and the crystal structure determined. Single crystal XRD revealed three crystallographically independent molecules in the unit cell. The geometry around each Cu(II) is square pyramidal with monodentate pyridine at the apical and bidentate carboxylates in equatorial positions. The supramolecular structure of the complex arises primarily as a result of C-H• • • O along with some contribution of C-H• • • C interactions, resulting in the preferential alignment of the molecules along the c-axis. The purity of the crystalline complex has been confirmed through powder XRD study. Electrochemical solution study of the complex in aqueous DMSO (1:4) showed two redox couples corresponding to Cu(III)/Cu(II) and Cu(II)/Cu(I) irreversible electron transfer. The values of various voltammetric variables such as diffusion coefficient (Do), heterogeneous rate constant (k°), formal potential (E Ì) and charge transfer coefficient (α) have been calculated before and after DNA addition. DNA binding of the complex has been explored through cyclic voltammetry, UV-Visible spectrophotometry and viscosity measurement which have exhibited a mixed electrostatic and intercalative mode of interaction. Cyclic voltammetry indicated self-induced redox activation and potential anticancer ability of the complex, supported by UV-Visible spectrophotometry as well as viscometry.
Details
- Title
- Synthesis, crystal structure description, electrochemical and DNA binding studies of ‘paddlewheel’ copper(II) carboxylate
- Authors
- Muhammad Iqbal (Author) - Quaid-i-Azam University, PakistanSaqib Ali (Author) - Quaid-i-Azam University, PakistanZia-Ur-Rehman (Author) - Quaid-i-Azam University, PakistanNiaz Muhammad (Author) - Abdul Wali Khan University, PakistanManzar Sohail (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and EngineeringVedapriya Pandarinathan (Author) - Curtin University
- Publication details
- Journal of Coordination Chemistry, Vol.67(10), pp.1731-1745
- Publisher
- Taylor & Francis Ltd.
- Date published
- 2014
- DOI
- 10.1080/00958972.2014.926337
- ISSN
- 0095-8972
- Copyright note
- Copyright © 2014 The Authors. This is an electronic version of an article published in Muhammad Iqbal, Saqib Ali, Zia-Ur Rehman, Niaz Muhammad, Manzar Sohail & Vedapriya Pandarinathan (2014) Synthesis, crystal structure description, electrochemical, and DNA-binding studies of "paddlewheel" copper(II) carboxylate, Journal of Coordination Chemistry, 67:10, 1731-1745, DOI: 10.1080/00958972.2014.926337 . Journal of Coordination Chemistry is available online at: http://www.tandfonline.com/openurl?genre=article&issn=0095-8972&volume=67&issue=10&spage=1731
- Organisation Unit
- School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland
- Language
- English
- Record Identifier
- 99448840702621
- Output Type
- Journal article
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