Synthesis, characterization of mixed ligand palladium(II) complexes of triphenylphosphine and anilines and their enzyme inhibition studies against β-glucuronidase. the crystal structure of trans-dichloro-(m-chloroaniline) (triphenylphosphine)palladium(II)

M Asma; A Badshah; Saqib Ali; Manzar Sohail; M Fettouhi; S Ahmad; A Malik

doi:10.1007/s11243-006-0027-z

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Synthesis, characterization of mixed ligand palladium(II) complexes of triphenylphosphine and anilines and their enzyme inhibition studies against β-glucuronidase. the crystal structure of trans-dichloro-(m-chloroaniline) (triphenylphosphine)palladium(II)

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Synthesis, characterization of mixed ligand palladium(II) complexes of triphenylphosphine and anilines and their enzyme inhibition studies against β-glucuronidase. the crystal structure of trans-dichloro-(m-chloroaniline) (triphenylphosphine)palladium(II)

M Asma, A Badshah, Saqib Ali, Manzar Sohail, M Fettouhi, S Ahmad and A Malik

Transition Metal Chemistry, Vol.31(4), pp.556-559

2006

DOI: https://doi.org/10.1007/s11243-006-0027-z

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Abstract

Inorganic Chemistry

amines

chemical bonds

crystal structure

enzyme inhibition

bond angles

glucuronidase

ligands

palladium compounds

A number of palladium(II) complexes with Ph 3P and aromatic amines as ligands having the general formula [(Ph 3P)Pd(Ph 3P)(NH 2R)Cl 2] {where R = Ph (1), m-ClC 6H 4 (2), p-ClC 6H 5 (3)} and [Pd(CH 3NHPh)Cl 2] (4), have been synthesized and characterized by elemental analysis, IR, 1H and 13C NMR. The X-ray crystal structure of [(Ph 3P)Pd(m-ClC 6H 4NH 2)Cl 2] . CH 2 Cl 2 (2) shows a distorted square planar environment around the Pd(II) ion with the P-Pd-N and Cl(1)-Pd-Cl(2) bond angles of 174.88(5)° and 176.77(2)° respectively. The complexes were screened for enzyme inhibition activity against β-glucuronidase and found to be active.

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Title: Synthesis, characterization of mixed ligand palladium(II) complexes of triphenylphosphine and anilines and their enzyme inhibition studies against β-glucuronidase. the crystal structure of trans-dichloro-(m-chloroaniline) (triphenylphosphine)palladium(II)
Authors: M Asma (Author) - Quaid-i-Azam University, Pakistan
A Badshah (Author) - Quaid-i-Azam University, Pakistan
Saqib Ali (Author) - Quaid-i-Azam University, Pakistan
Manzar Sohail (Author) - Quaid-i-Azam University, Pakistan
M Fettouhi (Author) - University of Petroleum and Minerals, Saudi Arabia
S Ahmad (Author) - University of Engineering and Technology, Pakistan
A Malik (Author) - University of Karachi, Pakistan
Publication details: Transition Metal Chemistry, Vol.31(4), pp.556-559
Publisher: Springer Netherlands
Date published: 2006
DOI: 10.1007/s11243-006-0027-z
ISSN: 0340-4285
Organisation Unit: School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland
Language: English
Record Identifier: 99448811402621
Output Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Chemistry, Inorganic & Nuclear

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