Sunlight and other determinants of circulating 25-hydroxyvitamin D levels in black and white participants in a nationwide US study

D M Freedman; E K Cahoon; P Rajaraman; J M Major; M M Doody; B H Alexander; R W Hoffbeck; Michael G Kimlin; B I Graubard; M S Linet

doi:10.1093/aje/kws223

Back

Sunlight and other determinants of circulating 25-hydroxyvitamin D levels in black and white participants in a nationwide US study

Journal article

Peer reviewed

Sunlight and other determinants of circulating 25-hydroxyvitamin D levels in black and white participants in a nationwide US study

D M Freedman, E K Cahoon, P Rajaraman, J M Major, M M Doody, B H Alexander, R W Hoffbeck, Michael G Kimlin, B I Graubard and M S Linet

American Journal of Epidemiology, Vol.177(2), pp.180-192

2013

DOI: https://doi.org/10.1093/aje/kws223

Files and links (1)

url

https://doi.org/10.1093/aje/kws223View

Published Version

Abstract

dietary supplements

25-hydroxyvitamin D

race

seasons

sex

sunlight

ultraviolet rays

vitamin D

Circulating 25-hydroxyvitamin D (25(OH)D), a marker for vitamin D status, is associated with bone health and possibly cancers and other diseases; yet, the determinants of 25(OH)D status, particularly ultraviolet radiation (UVR) exposure, are poorly understood. Determinants of 25(OH)D were analyzed in a subcohort of 1,500 participants of the US Radiologic Technologists (USRT) Study that included whites (n = 842), blacks (n = 646), and people of other races/ethnicities (n = 12). Participants were recruited monthly (2008-2009) across age, sex, race, and ambient UVR level groups. Questionnaires addressing UVR and other exposures were generally completed within 9 days of blood collection. The relation between potential determinants and 25(OH)D levels was examined through regression analysis in a random two-thirds sample and validated in the remaining one third. In the regression model for the full study population, age, race, body mass index, some seasons, hours outdoors being physically active, and vitamin D supplement use were associated with 25(OH)D levels. In whites, generally, the same factors were explanatory. In blacks, only age and vitamin D supplement use predicted 25(OH)D concentrations. In the full population, determinants accounted for 25% of circulating 25(OH)D variability, with similar correlations for subgroups. Despite detailed data on UVR and other factors near the time of blood collection, the ability to explain 25(OH)D was modest. © 2012 The Author.

Details

Title: Sunlight and other determinants of circulating 25-hydroxyvitamin D levels in black and white participants in a nationwide US study
Authors: D M Freedman (Author)
E K Cahoon (Author)
P Rajaraman (Author)
J M Major (Author)
M M Doody (Author)
B H Alexander (Author)
R W Hoffbeck (Author)
Michael G Kimlin (Author)
B I Graubard (Author)
M S Linet (Author)
Publication details: American Journal of Epidemiology, Vol.177(2), pp.180-192
Publisher: Oxford University Press
Date published: 2013
DOI: 10.1093/aje/kws223
ISSN: 0002-9262
Organisation Unit: University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy
Language: English
Record Identifier: 99450105502621
Output Type: Journal article

Metrics

560 Record Views

65 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Public, Environmental & Occupational Health

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: InCites