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Sulfur-adlayer-coated gold electrode for the in vitro electrochemical detection of uric acid in urine
Journal article   Peer reviewed

Sulfur-adlayer-coated gold electrode for the in vitro electrochemical detection of uric acid in urine

M R Miah, Muhammad Tanzirul Alam and T Ohsaka
Analytica Chimica Acta, Vol.669(1-2), pp.75-80
2010
url
https://doi.org/10.1016/j.aca.2010.04.048View
Published Version

Abstract

adsorption sulfur-adlayer uric acid enhanced selective electrooxidation
The present article demonstrates the electrochemical oxidation of uric acid (UA) at sulfur-adlayer-coated gold (S-Au) electrode in alkaline media. At S-Au electrode, UA oxidized at a significantly lower overpotential with a higher current density as compared to the bare Au electrode. The oxidation of UA at the S-Au electrode is highly selective in the presence of the other commonly existing bio-molecules in urine. The proposed electrochemical sensor not only exhibited good reproducibility, but also showed a fast amperometric response to UA in the concentration range of 0.0025-5 mM with a low detection limit of 0.4 μM.

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Chemistry, Analytical

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