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Structure and proteomic analysis of the crown-of-thorns starfish (Acanthaster sp.) radial nerve cord3.34 MB
Published VersionCC BY V4.0, Open Access
CorrectionCC BY V4.0, Open Access
Journal article
Structure and proteomic analysis of the crown-of-thorns starfish (Acanthaster sp.) radial nerve cord
Scientific Reports, Vol.13(1), pp.1-12
2023
PMID: 36849815
Abstract
The nervous system of the Asteroidea (starfish or seastar) consists of radial nerve cords (RNCs) that interconnect with a ring nerve. Despite its relative simplicity, it facilitates the movement of multiple arms and numerous tube feet, as well as regeneration of damaged limbs. Here, we investigated the RNC ultrastructure and its molecular components within the of Pacific crown of thorns starfish (COTS; Acanthaster sp.), a well known coral predator that in high density outbreaks has major ecological impacts on coral reefs. We describe the presence of an array of unique small bulbous bulbs (40–100 μm diameter) that project from the ectoneural region of the adult RNC. Each comprise large secretory like cells and prominent cilia. In contrast, juvenile COTS and its congener Acanthaster brevispinus lack these features, both of which are non corallivorous. Proteomic analysis of the RNC (and isolated neural bulbs) provides the first comprehensive echinoderm protein database for neural tissue, including numerous secreted proteins associated with signalling, transport and defence. The neural bulbs contained several neuropeptides (e.g., bombyxin type, starfish myorelaxant peptide, secretogranin 7B2 like, Ap15a like, and ApNp35) and Deleted in Malignant Brain Tumor 1 like proteins. In summary, this study provides a new insight into the novel traits of COTS, a major pest on coral reefs, and a proteomics resource that can be used to develop (bio)control strategies and understand molecular mechanisms of regeneration.
Details
- Title
- Structure and proteomic analysis of the crown-of-thorns starfish (Acanthaster sp.) radial nerve cord
- Authors
- Meaghan K. Smith (Author) - University of the Sunshine Coast, Queensland, Centre for BioinnovationBronwyn A. Rotgans (Author) - University of the Sunshine Coast, Queensland, Centre for BioinnovationTomas Lang (Author) - University of the Sunshine Coast, Queensland, Centre for BioinnovationRyan Johnston (Author) - University of the Sunshine Coast, Queensland, Centre for BioinnovationTianfang Wang (Author) - University of the Sunshine Coast, Queensland, Centre for BioinnovationSaowaros Suwansa-ard (Author) - University of the Sunshine Coast, Queensland, Centre for BioinnovationUtpal Bose (Author) - University of the Sunshine Coast, Queensland, Centre for BioinnovationNori Satoh (Author) - Okinawa Institute of Science and TechnologyMichaela Egertova (Author) - Queen Mary University of LondonMichael R. Hall (Author) - Australian Institute of Marine ScienceMaria Bryne (Author) - The University of SydneyMaurice R. Elphick (Author) - Queen Mary University of LondonCherie A. Motti (Author) - Australian Institute of Marine ScienceScott F. Cummins (Author) - University of the Sunshine Coast, Queensland, Centre for Bioinnovation
- Publication details
- Scientific Reports, Vol.13(1), pp.1-12
- Publisher
- Nature Publishing Group
- Date published
- 2023
- DOI
- 10.1038/s41598-023-30425-1
- ISSN
- 2045-2322
- PMID
- 36849815
- Copyright note
- This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. Te images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
- Grant note
- BB/M001644/1 / BBSRC RPG-2013-351 / Leverhulme Trust Australian Postgraduate Award scholarship
- Organisation Unit
- School of Health - Biomedicine; Faculty of Science, Health, Education and Engineering; School of Science and Engineering - Legacy; GeneCology Research Centre - Legacy; School of Science, Technology and Engineering; Centre for Bioinnovation
- Language
- English
- Record Identifier
- 99710097602621
- Output Type
- Journal article
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