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Social decision making in autism - On the impact of mirror neurons, motor control, and imitative behaviors695.86 kB
Published VersionCC BY-NC V4.0, Open Access
Journal article
Social decision making in autism: On the impact of mirror neurons, motor control, and imitative behaviors
CNS Neuroscience & Therapeutics, Vol.24(8), pp.669-676
2018
PMCID: PMC6055683
PMID: 29963752
Abstract
The Mirror Neuron System (MNS) plays a crucial role in action perception and imitative behavior, which is suggested to be impaired in Autism Spectrum Disorders (ASDs). In this review, we discuss the plausibility and empirical evidence of a neural interaction between the MNS, action perception, empathy, imitative behavior, and their impact on social decision making in ASDs. To date, there is no consensus regarding a particular theory in ASDs and its underlying mechanisms. Some theories have completely focused on social difficulties, others have emphasized sensory aspects. Based on the current studies, we suggest a multilayer neural network model including the MNS on a first layer and transforming this information to a higher layer network responsible for reasoning. Future studies with ASD participants combining behavioral tasks with neuroimaging methods and transcranial brain stimulation as well as computational modeling can help validate and complement this suggested model. Moreover, we propose applying the behavioral paradigms, and the neurophysiological markers mentioned in this review article for evaluating psychiatric treatment approaches in ASDs. The investigation of modulating effects of different treatment approaches on the neurophysiological markers of the MNS can help find specific subgroups of ASDs patients and support tailored psychiatric interventions.
Details
- Title
- Social decision making in autism: On the impact of mirror neurons, motor control, and imitative behaviors
- Authors
- Radwa Khalil (Corresponding Author) - Constructor UniversityRichard Tindle (Author) - CanteenThomas Boraud (Author) - Université de BordeauxAhmed A Moustafa (Author) - Western Sydney UniversityAhmed A Karim (Corresponding Author) - SRH Fernhochschule Riedlingen
- Publication details
- CNS Neuroscience & Therapeutics, Vol.24(8), pp.669-676
- Publisher
- Wiley-Blackwell Publishing Ltd.
- Date published
- 2018
- DOI
- 10.1111/cns.13001
- ISSN
- 1755-5949; 1755-5930
- PMID
- 29963752; PMC6055683
- Copyright note
- This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. © 2018 The Authors. CNS Neuroscience & Therapeutics Published by John Wiley & Sons Ltd
- Organisation Unit
- Indigenous and Transcultural Research Centre; University of the Sunshine Coast, Queensland; School of Health and Behavioural Sciences - Legacy
- Language
- English
- Record Identifier
- 99557708402621
- Output Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web Of Science research areas
- Neurosciences
- Pharmacology & Pharmacy