Journal article
Sleep–wake profiles predict longitudinal changes in manic symptoms and memory in young people with mood disorders
Journal of Sleep Research, Vol.25(5), pp.549-555
2016
Abstract
Mood disorders are characterized by disabling symptoms and cognitive difficulties which may vary in intensity throughout the course of the illness. Sleep-wake cycles and circadian rhythms influence emotional regulation and cognitive functions. However, the relationships between the sleep-wake disturbances experienced commonly by people with mood disorders and the longitudinal changes in their clinical and cognitive profile are not well characterized. This study investigated associations between initial sleep-wake patterns and longitudinal changes in mood symptoms and cognitive functions in 50 young people (aged 13-33 years) with depression or bipolar disorder. Data were based on actigraphy monitoring conducted over approximately 2 weeks and clinical and neuropsychological assessment. As part of a longitudinal cohort study, these assessments were repeated after a mean follow-up interval of 18.9 months. No significant differences in longitudinal clinical changes were found between the participants with depression and those with bipolar disorder. Lower sleep efficiency was predictive of longitudinal worsening in manic symptoms (P = 0.007). Shorter total sleep time (P = 0.043) and poorer circadian rhythmicity (P = 0.045) were predictive of worsening in verbal memory. These findings suggest that some sleep-wake and circadian disturbances in young people with mood disorders may be associated with less favourable longitudinal outcomes, notably for subsequent manic symptoms and memory difficulties. © 2016 European Sleep Research Society
Details
- Title
- Sleep–wake profiles predict longitudinal changes in manic symptoms and memory in young people with mood disorders
- Authors
- R Robillard (Author) - University of SydneyDaniel F Hermens (Author) - University of SydneyR S C Lee (Author) - University of SydneyA Jones (Author) - University of SydneyJ S Carpenter (Author) - University of SydneyD White (Author) - University of SydneyS L Naismith (Author) - University of SydneyJ Southan (Author) - University of SydneyB Whitwell (Author) - University of SydneyE M Scott (Author) - University of SydneyI B Hickie (Author) - University of Sydney
- Publication details
- Journal of Sleep Research, Vol.25(5), pp.549-555
- Publisher
- Wiley-Blackwell Publishing Ltd.
- DOI
- 10.1111/jsr.12413
- ISSN
- 0962-1105
- Organisation Unit
- Thompson Institute; University of the Sunshine Coast, Queensland
- Language
- English
- Record Identifier
- 99450365202621
- Output Type
- Journal article
Metrics
3215 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Web Of Science research areas
- Clinical Neurology
- Neurosciences
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites