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Sleep-Wake cycle and melatonin rhythms in adolescents and young adults with mood disorders: Comparison of unipolar and bipolar phenotypes
Journal article   Peer reviewed

Sleep-Wake cycle and melatonin rhythms in adolescents and young adults with mood disorders: Comparison of unipolar and bipolar phenotypes

R Robillard, S L Naismith, N L Rogers, E M Scott, T K C Ip, Daniel F Hermens and I B Hickie
European Psychiatry, Vol.28(7), pp.412-416
2013
url
https://doi.org/10.1016/j.eurpsy.2013.04.001View
Published Version

Abstract

depression bipolar disorder circadian melatonin actigraphy core body temperature
This study evaluated the potential of circadian measures as early markers of mood disorders subtypes. Patients with bipolar disorders had significantly lower levels and later onset of melatonin secretion than those with unipolar depression. Furthermore, abnormal phase angles between sleep, melatonin and temperature were found in several patients. © 2013 Elsevier Masson SAS.

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Psychiatry

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