Six-Minute Walk Distance Predicts VO2 (max) in Patients Supported with Continuous Flow Left Ventricular Assist Devices

Roslyn A Prichard; Marcus Juul; Gary Gazibarich; Patricia M Davidson; Carmel Mason; Anne M Keogh; Peter S Macdonald; Christopher S Hayward

doi:10.5301/ijao.5000345

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Six-Minute Walk Distance Predicts VO2 (max) in Patients Supported with Continuous Flow Left Ventricular Assist Devices

Journal article

Peer reviewed

Six-Minute Walk Distance Predicts VO2 (max) in Patients Supported with Continuous Flow Left Ventricular Assist Devices

Roslyn A Prichard, Marcus Juul, Gary Gazibarich, Patricia M Davidson, Carmel Mason, Anne M Keogh, Peter S Macdonald and Christopher S Hayward

International Journal of Artificial Organs, Vol.37(7), pp.539-545

2014

DOI: https://doi.org/10.5301/ijao.5000345

PMID: 25044385

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Abstract

Exercise test

Cardiopulmonary exercise test

Six Minute Walk Test

Cardiomyopathies

Heart-Assist devices

Ventricular-Assist Devices

Maximal Oxygen uptake (VO2 max)

Background: Six-minute walk distance (6MWD) and maximal oxygen uptake (VO2 max) are used as prognostic tools in patients with heart failure (HF). Whether these tests provide similar information in the LVAD population is not known. Methods: Eight patients supported with VentrAssist rotary blood pump LVADs, underwent three days of testing that included 6MWD and VO2 max at normal, high or low speeds, generating twenty-four paired results. Results: The mean 6MWD was 438 (+/- 90 SD) m and the mean VO2 was 14.12 (+/-1.87) ml/kg/min. There was a modest correlation between VO2(max) and 6MWD (r = 0.56 p = 0.004), which improved (r = 0.72 p = 0.002) when patients with higher resting Pro BNP levels and larger left ventricular end diastolic diameters (LVEDD) were excluded. Conclusions: 6MWD is correlated with VO2 (max) in LVAD supported patients, with higher correlations in patients with better underlying cardiac function.

Details

Title: Six-Minute Walk Distance Predicts VO2 (max) in Patients Supported with Continuous Flow Left Ventricular Assist Devices
Authors: Roslyn A Prichard (Author) - University of Technology Sydney
Marcus Juul (Author) - Heart Failure and Transplant Unit, St Vincent's Hospital, Sydney - Australia
Gary Gazibarich (Author) - Heart Failure and Transplant Unit, St Vincent's Hospital, Sydney - Australia
Patricia M Davidson (Author) - University of Technology Sydney
Carmel Mason (Author) - University of Sydney
Anne M Keogh (Author) - Heart Failure and Transplant Unit, St Vincent's Hospital, Sydney - Australia
Peter S Macdonald (Author) - Heart Failure and Transplant Unit, St Vincent's Hospital, Sydney - Australia
Christopher S Hayward (Author) - Heart Failure and Transplant Unit, St Vincent's Hospital, Sydney - Australia
Publication details: International Journal of Artificial Organs, Vol.37(7), pp.539-545
Publisher: Sage Publication Ltd.
DOI: 10.5301/ijao.5000345
ISSN: 1724-6040
PMID: 25044385
Organisation Unit: University of the Sunshine Coast, Queensland; School of Nursing, Midwifery and Paramedicine - Legacy; School of Health - Nursing
Language: English
Record Identifier: 99512808502621
Output Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Engineering, Biomedical; Transplantation

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