Selenium Status: Its Interactions with Dietary Mercury Exposure and Implications in Human Health

Ujang Tinggi; Anthony V Perkins

doi:10.3390/nu14245308

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Selenium Status: Its Interactions with Dietary Mercury Exposure and Implications in Human Health

Journal article

Open access

Peer reviewed

Selenium Status: Its Interactions with Dietary Mercury Exposure and Implications in Human Health

Ujang Tinggi and Anthony V Perkins

Nutrients, Vol.14(24), pp.1-19

2022

DOI: https://doi.org/10.3390/nu14245308

PMCID: PMC9785339

PMID: 36558469

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Abstract

dietary intakes

blood levels

trace elements

selenium

mercury

Selenium is an essential trace element in humans and animals and its role in selenoprotein and enzyme antioxidant activity is well documented. Food is the principal source of selenium, and it is important that selenium status in the body is adequately maintained for physiological functions. There has been increasing attention on the role of selenium in mitigating the toxic effects of mercury exposure from dietary intake in humans. In contrast, mercury is a neurotoxin, and its continuous exposure can cause adverse health effects in humans. The interactions of selenium and mercury are multi-factorial and involve complex binding mechanisms between these elements at a molecular level. Further insights and understanding in this area may help to evaluate the health implications of dietary mercury exposure and selenium status. This review aims to summarise current information on the interplay of the interactions between selenium and mercury in the body and the protective effect of selenium on at-risk groups in a population who may experience long-term mercury exposure.

Details

Title: Selenium Status: Its Interactions with Dietary Mercury Exposure and Implications in Human Health
Authors: Ujang Tinggi (Corresponding Author) - Queensland Health Forensic and Scientific Services
Anthony V Perkins (Author) - University of the Sunshine Coast, Queensland, School of Health and Behavioural Sciences - Legacy
Publication details: Nutrients, Vol.14(24), pp.1-19
Publisher: MDPI AG
Date published: 2022
DOI: 10.3390/nu14245308
ISSN: 2072-6643
PMID: 36558469; PMC9785339
Copyright note: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Organisation Unit: School of Health; School of Health and Behavioural Sciences - Legacy
Language: English
Record Identifier: 99696659802621
Output Type: Journal article

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Collaboration types: Domestic collaboration
Web Of Science research areas: Nutrition & Dietetics