Journal article
Seasonal changes in haematology, lymphocyte transferrin receptors and intracellular iron in Ironman triathletes and untrained men
European Journal of Applied Physiology, Vol.111(1), pp.93-100
2011
Abstract
We investigated whether 12 months of chronic endurance training would affect haematology, CD4 + lymphocyte transferrin receptor (CD71) expression, CD4 + intracellular iron and the incidence of upper respiratory tract illnesses (URTI) in Ironman triathletes compared with untrained men. Resting venous blood samples were taken from 15 Ironman triathletes (TR 30±5 year) and 12 untrained men (UT 30±6 year) every 4 weeks for 12 months. Erythrocyte, leukocyte and platelet concentration, haematocrit, haemoglobin (Hb) and mean corpuscular haemoglobin (MCHC) were measured with a full blood count. CD4 + lymphocytes were analysed for changes in transferrin receptor (CD71) expression (CD4 +CD71 +), and intracellular iron (Fe 3+), by flow cytometry. The TR group had significantly lower Hb, MCHC, and platelets for 10, 9 and 11 months, respectively; lower CD4 +CD71 + (3 months) and Fe 3+ (1 month), respectively; higher CD4 +CD71 + (1 month); a higher lymphocyte count for 4 months. There were no between-group differences in other variables. In both groups haematology and lymphocytes increased during spring, early summer and winter and decreased during late summer/late winter, with an inverse relationship between CD4 +CD71 + and Fe 3+. The TR group reported significantly fewer URTI than the UT. Low Hb and MCHC suggest an iron deficiency which may affect triathlete performance. Monthly changes in lymphocytes, CD4 +CD71 + and Fe 3+ suggested that spring, summer and late autumn are associated with CD4 + proliferation. There may be seasonal relationships between haematology and lymphocyte function, independent of endurance training, possibly affecting performance but not the incidence of URTI. © 2010 Springer-Verlag.
Details
- Title
- Seasonal changes in haematology, lymphocyte transferrin receptors and intracellular iron in Ironman triathletes and untrained men
- Authors
- Suzanne Broadbent (Author) - Victoria University
- Publication details
- European Journal of Applied Physiology, Vol.111(1), pp.93-100
- Publisher
- Springer
- Date published
- 2011
- DOI
- 10.1007/s00421-010-1635-z
- ISSN
- 1439-6319
- Organisation Unit
- University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy; School of Health - Sports & Exercise Science; School of Health and Behavioural Sciences - Legacy
- Language
- English
- Record Identifier
- 99450419702621
- Output Type
- Journal article
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