Logo image
Back
Scabies: Molecular Perspectives and Therapeutic Implications in the Face of Emerging Drug Resistance
Journal article   Peer reviewed

Scabies: Molecular Perspectives and Therapeutic Implications in the Face of Emerging Drug Resistance

Kate E Mounsey, D C Holt, J McCarthy, B J Currie and Shelley F Walton
Future Microbiology, Vol.3(1), pp.57-66
2008
DOI: https://doi.org/10.2217/17460913.3.1.57
url
https://doi.org/10.2217/17460913.3.1.57View
Published Version

Abstract

Sarcoptes scabiei scabies drug resistance
Limited effective treatments, coupled with recent observations of emerging drug resistance to oral ivermectin and 5% permethrin, raise concerns regarding the future control of scabies, especially in severe cases and in endemic areas where repeated community treatment programs are in place. There is consequently an urgent need to define molecular mechanisms of drug resistance in scabies mites and to develop and assess alternative therapeutic options, such as tea tree oil, in the event of increasing treatment failure. Molecular studies on scabies mites have, until recently, been restricted; however, recent advances are providing new insights into scabies mite biology and genetic mechanisms underlying drug resistance. These may assist in overcoming many of the current difficulties in monitoring treatment efficacy and allow the development of more sensitive tools for monitoring emerging resistance.

Details

Metrics

2 File views/ downloads
472 Record Views
78 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types
Domestic collaboration
Web Of Science research areas
Microbiology

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

Source: InCites

Logo image