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Adv Materials Inter - 2023 - Saifullah - Sampling Dermal Interstitial Fluid Using Microneedles A Review of Recent3.85 MB
Published VersionCC BY V4.0, Open Access
Journal article
Sampling Dermal Interstitial Fluid Using Microneedles: A Review of Recent Developments in Sampling Methods and Microneedle‐Based Biosensors
Advanced Materials Interfaces, Vol.10(10), pp.1-23
2023
Abstract
Although interstitial fluid (ISF) is recognized as an important source of biomarkers, it is difficult and time‐consuming to extract, thus limiting its use in medical diagnostic and clinical settings. An inexpensive and effective technique for accessing ISF could benefit people with various health conditions and offer platforms for on‐device sensing biomarkers. Microneedles (MNs) are minimally invasive devices that have gained extensive interest over recent decades. MNs can address some of the challenges associated with ISF extraction and sensing. Accessing ISF using MNs has the potential to develop advanced, non‐invasive point‐of‐care (POC) microdevices that enable detection or continuous monitoring within the dermal ISF, therefore drastically impacting the healthcare system. This review describes recent studies exploring MN devices for ISF sampling and sensing. Several extraction processes, sampling volume, sampling duration, integration with biosensors, sensing of biomarkers, and subsequent analysis of ISF are discussed in detail. Furthermore, opportunities, conclusions, and future prospects for developing new research in the field are also discussed. Interstitial fluid is recognized as an important source of biomarkers; however, it is difficult and time‐consuming to extract, thus limiting its use in medical diagnostic and clinical settings. Microneedles are minimally invasive devices that have gained extensive interest over recent decades. Microneedles can address some of the challenges associated with ISF extraction and sensing.
Details
- Title
- Sampling Dermal Interstitial Fluid Using Microneedles: A Review of Recent Developments in Sampling Methods and Microneedle‐Based Biosensors
- Authors
- Khaled Mohammed Saifullah (Corresponding Author) - University of Southern QueenslandZahra Faraji Rad (Corresponding Author) - University of Southern Queensland
- Publication details
- Advanced Materials Interfaces, Vol.10(10), pp.1-23
- Publisher
- Wiley-VCH Verlag GmbH & Co. KGaA
- Date published
- 2023
- DOI
- 10.1002/admi.202201763
- ISSN
- 2196-7350
- Copyright note
- © 2023 The Authors. Advanced Materials Interfaces published by Wiley-VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Organisation Unit
- School of Science, Technology and Engineering
- Language
- English
- Record Identifier
- 991140306002621
- Output Type
- Journal article
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- Chemistry, Multidisciplinary
- Materials Science, Multidisciplinary
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