Recent Advances in the Development of Antimicrobial Nanoparticles for Combating Resistant Pathogens

R Lakshminarayanan; E Ye; David James Young; Z Li; X J Loh

doi:10.1002/adhm.201701400

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Recent Advances in the Development of Antimicrobial Nanoparticles for Combating Resistant Pathogens

Journal article

Peer reviewed

Recent Advances in the Development of Antimicrobial Nanoparticles for Combating Resistant Pathogens

R Lakshminarayanan, E Ye, David James Young, Z Li and X J Loh

Advanced Healthcare Materials, Vol.7(13), pp.1-13

2018

DOI: https://doi.org/10.1002/adhm.201701400

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Abstract

antimicrobial

formulations

nanoparticles

pathogens

resistant

The rapid growth of harmful pathogens and their multidrug-resistance poses a severe challenge for health professionals and for the development of new healthcare products. Various strategies are exploited for the development of effective antimicrobial agents, and nanoparticles are a particularly promising class of materials in this respect. This review summarizes recent advances in antimicrobial metallic, polymeric, and lipid-based nanoparticles such as liposomes, solid lipid nanoparticles, and nanostructured lipid carriers. The latter materials in particular are engineered for antimicrobial agent delivery and act by encapsulation, receptor-based binding, and disruption of microbial adherence to cellular substrates. Potential strategies for the design of multifunctional antimicrobial nanocarriers, combining material chemistry and biological interface science, are also discussed. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Details

Title: Recent Advances in the Development of Antimicrobial Nanoparticles for Combating Resistant Pathogens
Authors: R Lakshminarayanan (Corresponding Author) - Singapore Eye Research Institute, Singapore
E Ye (Author) - Institute of Materials Research and Engineeering, Singapore
David James Young (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and Engineering
Z Li (Corresponding Author) - Institute of Materials Research and Engineeering, Singapore
X J Loh (Corresponding Author) - Singapore Eye Research Institute, Singapore
Publication details: Advanced Healthcare Materials, Vol.7(13), pp.1-13
Publisher: Wiley - V C H Verlag GmbH & Co. KGaA
Date published: 2018
DOI: 10.1002/adhm.201701400
ISSN: 2192-2640
Organisation Unit: University of the Sunshine Coast, Queensland
Language: English
Record Identifier: 99450642702621
Output Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Engineering, Biomedical; Materials Science, Biomaterials; Nanoscience & Nanotechnology

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