Randomized controlled trial of a healthy brain ageing cognitive training program: effects on memory, mood, and sleep

K Diamond; L Mowszowski; N Cockayne; L Norrie; M Paradise; Daniel F Hermens; S J Lewis; I B Hickie; S L Naismith

doi:10.3233/JAD-142061

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Randomized controlled trial of a healthy brain ageing cognitive training program: effects on memory, mood, and sleep

Journal article

Peer reviewed

Randomized controlled trial of a healthy brain ageing cognitive training program: effects on memory, mood, and sleep

K Diamond, L Mowszowski, N Cockayne, L Norrie, M Paradise, Daniel F Hermens, S J Lewis, I B Hickie and S L Naismith

Journal of Alzheimer's Disease, Vol.44(4), pp.1181-1191

2015

DOI: https://doi.org/10.3233/JAD-142061

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Abstract

depression

memory

mild cognitive impairment

neuropsychology

sleep disorders

BACKGROUND: With the rise in the ageing population and absence of a cure for dementia, cost-effective prevention strategies for those 'at risk' of dementia including those with depression and/or mild cognitive impairment are urgently required. OBJECTIVE: This study evaluated the efficacy of a multifaceted Healthy Brain Ageing Cognitive Training (HBA-CT) program for older adults 'at risk' of dementia. METHODS: Using a single-blinded design, 64 participants (mean age = 66.5 years, SD = 8.6) were randomized to an immediate treatment (HBA-CT) or treatment-as-usual control arm. The HBA-CT intervention was conducted twice-weekly for seven weeks and comprised group-based psychoeducation about cognitive strategies and modifiable lifestyle factors pertaining to healthy brain ageing, and computerized cognitive training. RESULTS: In comparison to the treatment-as-usual control arm, the HBA-CT program was associated with improvements in verbal memory (p = 0.03), self-reported memory (p = 0.03), mood (p = 0.01), and sleep (p = 0.01). While the improvements in memory (p = 0.03) and sleep (p = 0.02) remained after controlling for improvements in mood, only a trend in verbal memory improvement was apparent after controlling for sleep. CONCLUSION: The HBA-CT program improves cognitive, mood, and sleep functions in older adults 'at risk' of dementia, and therefore offers promise as a secondary prevention strategy.

Details

Title: Randomized controlled trial of a healthy brain ageing cognitive training program: effects on memory, mood, and sleep
Authors: K Diamond (Author)
L Mowszowski (Author)
N Cockayne (Author)
L Norrie (Author)
M Paradise (Author)
Daniel F Hermens (Author) - University of Sydney
S J Lewis (Author)
I B Hickie (Author)
S L Naismith (Author)
Publication details: Journal of Alzheimer's Disease, Vol.44(4), pp.1181-1191
Publisher: IOS Press
Date published: 2015
DOI: 10.3233/JAD-142061
ISSN: 1875-8908
Organisation Unit: University of the Sunshine Coast, Queensland; Thompson Institute
Language: English
Record Identifier: 99451285802621
Output Type: Journal article

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