Quantitative proteomic dataset of mouse caput epididymal epithelial cells exposed to acrylamide in vivo

Natalie A Trigg; David A Skerrett-Byrne; Jacinta Martin; Geoffry N De Iuliis; Matthew D Dun; Shaun D Roman; Andrew Eamens; Brett Nixon

doi:10.1016/j.dib.2022.108032

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Quantitative proteomic dataset of mouse caput epididymal epithelial cells exposed to acrylamide in vivo

Journal article

Open access

Peer reviewed

Quantitative proteomic dataset of mouse caput epididymal epithelial cells exposed to acrylamide in vivo

Natalie A Trigg, David A Skerrett-Byrne, Jacinta Martin, Geoffry N De Iuliis, Matthew D Dun, Shaun D Roman, Andrew Eamens and Brett Nixon

Data in Brief, Vol.42, pp.1-7

2022

DOI: https://doi.org/10.1016/j.dib.2022.108032

PMID: 35392627

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Abstract

Acrylamide

Epididymis

Epithelial cells

Proteome

Sperm maturation

This article reports the proteomic legacy of in vivo exposure to the xenobiotic, acrylamide, on the epithelial cell population of the proximal segments of the mouse epididymis. Specifically, adult male mice were administered acrylamide (25 mg/kg bw/day) or vehicle control for five consecutive days before dissection of the epididymis. Epididymal epithelial cells were isolated from the proximal (caput) epididymal segment and subjected to quantitative proteomic analysis using multiplexed tandem mass tag (TMT) labeling coupled to mass spectrometry. Here, we report the data generated by this strategy, including the identification of 4405 caput epididymal epithelial cell proteins, approximately 6.8% of which displayed altered expression in response to acrylamide challenge. Our interpretation and discussion of these data features in the article “Acrylamide modulates the mouse epididymal proteome to drive alterations in the sperm small non-coding RNA profile and dysregulate embryo development”

Details

Title: Quantitative proteomic dataset of mouse caput epididymal epithelial cells exposed to acrylamide in vivo
Authors: Natalie A Trigg (Author) - University of Newcastle Australia
David A Skerrett-Byrne (Author) - University of Newcastle Australia
Jacinta Martin (Author) - University of Newcastle Australia
Geoffry N De Iuliis (Author) - University of Newcastle Australia
Matthew D Dun (Author) - University of Newcastle Australia
Shaun D Roman (Author) - University of Newcastle Australia
Andrew Eamens (Author) - University of Newcastle Australia
Brett Nixon (Author) - University of Newcastle Australia
Publication details: Data in Brief, Vol.42, pp.1-7
Publisher: Elsevier BV
Date published: 2022
DOI: 10.1016/j.dib.2022.108032
ISSN: 2352-3409
PMID: 35392627
Organisation Unit: School of Health - Biomedicine; University of the Sunshine Coast, Queensland; School of Health and Behavioural Sciences - Legacy
Language: English
Record Identifier: 99656594202621
Output Type: Journal article

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Collaboration types: Domestic collaboration
Web Of Science research areas: Multidisciplinary Sciences

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