Quality of life in caregivers of patients randomized to standard versus extended hour hemodialysis

Melissa Nataatmadja; Rathika Krishnasamy; Li Zuo; Daqing Hong; Brendan Smyth; Min Jun; Janak R de Zoysa; Kirsten Howard; Jing Wang; Chunlai Lu; Zhangsuo Liu; Christopher T Chan; Alan Cass; Vlado Perkovic; Meg Jardine; Nicholas A Gray

doi:10.1016/j.ekir.2021.01.020

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Quality of life in caregivers of patients randomized to standard versus extended hour hemodialysis

Journal article

Open access

Peer reviewed

Quality of life in caregivers of patients randomized to standard versus extended hour hemodialysis

Melissa Nataatmadja, Rathika Krishnasamy, Li Zuo, Daqing Hong, Brendan Smyth, Min Jun, Janak R de Zoysa, Kirsten Howard, Jing Wang, Chunlai Lu, …

Kidney International Reports, Vol.6(4), pp.1058-1065

2021

DOI: https://doi.org/10.1016/j.ekir.2021.01.020

Appears in UniSC Diversity and Inclusion Research Collection

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Abstract

quality of life

hemodialysis

caregiver

extended dialysis

Co-ACTIVE

A Clinical Trial of Intensive Dialysis

UniSC Diversity Area - Life Stages

Introduction: Caregivers are essential for the health, safety and independence of many patients and incur financial and personal cost in this role, including increased burden and lower quality of life (QOL) compared to the general population. Extended hours hemodialysis may be the preference of some patients, but little is known about its effects on caregivers. Methods: Forty caregivers of participants of the ACTIVE Dialysis trial, who were randomized to 12 months extended (median 24 hours/week) or standard (12 hours/week) hemodialysis, were included. Utility-based QOL measured by EuroQOL-5 Dimension-3 Level (EQ-5D-3L) and Short Form-6D (SF-6D); and health related QOL (HRQOL) measured by Short Form-36 (SF-36) physical component summary (PCS) and mental component summary (MCS), and Personal Wellbeing Index (PWI) were measured at enrolment then every 3 months until end of study. Results: At baseline, utility-based QOL and HRQOL were similar in both groups. At follow-up, caregivers of people randomized to extended hours dialysis experienced a greater decrease in utility-based QOL measured by EQ-5D-3L compared to caregivers of people randomized to standard hours (-0.18±0.30 vs -0.02±0.16, p=0.04). There were no differences between extended and standard hours groups in mean change in SF-6D (0.03±0.12 vs -0.04±0.1, p=0.8), PCS (-1.2±9.8 vs -5.6±9.8, p=0.2), MCS (-4.1±11.2 vs -0.5±7.1, p=0.4), and PWI (2.3±17.6 vs 0.00±20.4, p=0.9). Conclusion: Poorer utility-based QOL, as measured by the EQ-5D-3L, was observed in caregivers of patients receiving extended hours hemodialysis in this small study. Though the findings are exploratory, the possibility that mode of dialysis delivery negatively impacts on caregivers supports the prioritization of research on burden and impact of service delivery in this population.

Details

Title: Quality of life in caregivers of patients randomized to standard versus extended hour hemodialysis
Authors: Melissa Nataatmadja (Author) - Sunshine Coast University Hospital
Rathika Krishnasamy (Author) - Sunshine Coast University Hospital
Li Zuo (Author) - Peking University People's Hospital
Daqing Hong (Author) - University of Electronic Science and Technology of China
Brendan Smyth (Author) - The University of Sydney
Min Jun (Author) - UNSW Australia
Janak R de Zoysa (Author) - University of Auckland
Kirsten Howard (Author) - The University of Sydney
Jing Wang (Author) - First Affiliated Hospital of Dalian Medical University
Chunlai Lu (Author) - Chinese People 's Liberation Army No. 85 Hospital
Zhangsuo Liu (Author) - First Affiliated Hospital of Zhengzhou University
Christopher T Chan (Author) - University Health Network
Alan Cass (Author) - Charles Darwin University
Vlado Perkovic (Author) - UNSW Australia
Meg Jardine (Author) - UNSW Australia
Nicholas A Gray (Author) - University of the Sunshine Coast, Queensland, School of Health and Sport Sciences - Legacy
Publication details: Kidney International Reports, Vol.6(4), pp.1058-1065
Publisher: Elsevier Inc.
Date published: 2021
DOI: 10.1016/j.ekir.2021.01.020
ISSN: 2468-0249
Organisation Unit: UniSC Clinical Trials Centre; School of Health and Sport Sciences - Legacy; School of Health and Behavioural Sciences - Legacy
Language: English
Record Identifier: 99508607602621
Output Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Urology & Nephrology

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