Pulmonary Histopathology in Cats and Dogs with Fatal Tick Paralysis

Yachen Wang; Natalie  Watters; Emily Jones; Andrew Padula; Ellie Leister; Mark  Haworth; Joerg Henning; Rachel Allavena

doi:10.1016/j.jcpa.2022.07.005

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Pulmonary Histopathology in Cats and Dogs with Fatal Tick Paralysis

Journal article

Peer reviewed

Pulmonary Histopathology in Cats and Dogs with Fatal Tick Paralysis

Yachen Wang, Natalie Watters, Emily Jones, Andrew Padula, Ellie Leister, Mark Haworth, Joerg Henning and Rachel Allavena

Journal of Comparative Pathology, Vol.197, pp.44-52

2022

DOI: https://doi.org/10.1016/j.jcpa.2022.07.005

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Abstract

histopathology

Ixodes

pulmonary oedema

tick paralysis

The objective of this study was to evaluate critically the nature and prevalence of histological pulmonary lesions in dogs and cats that had died or were euthanized because of tick paralysis. A retrospective and prospective case study of 11 cats and 23 dogs was carried out. Retrospective cases were gathered from the Veterinary Laboratory Services database at The University of Queensland (UQ). Prospective cases were provided by Veterinary Specialist Services and UQ VETs Small Animal Hospital. Lung and other tissue samples were collected for histopathological analysis. All tick intoxicated animals demonstrated evidence of pulmonary parenchymal changes: alveolar oedema, interstitial and alveolar congestion and alveolar fibrin exudation. Eleven of 23 (48%) dogs exhibited mild to severe bronchopneumonia. A lower rate (18%) of bronchopneumonia was found in cats, with one case of aspiration pneumonia. A novel pulmonary histological grading scheme was developed to evaluate the correlation between clinical presentation and histopathological changes. Novel extrapulmonary lesions in cats included hepatic necrosis and acute renal tubular necrosis attributed to hypoxia. We concluded that both dogs and cats with high clinical grade tick paralysis are extremely likely to have pulmonary pathology. High-protein oedema and fibrin exudation are predicted to be present in most cases of canine and feline tick paralysis.

Details

Title: Pulmonary Histopathology in Cats and Dogs with Fatal Tick Paralysis
Authors: Yachen Wang (Author) - University of the Sunshine Coast, Queensland, School of Science, Technology and Engineering
Natalie Watters (Author) - University of Queensland
Emily Jones (Corresponding Author) - University of Queensland
Andrew Padula (Author) - University of Melbourne
Ellie Leister (Author)
Mark Haworth (Author) - University of Queensland
Joerg Henning (Author) - University of Queensland
Rachel Allavena (Author) - University of Queensland
Publication details: Journal of Comparative Pathology, Vol.197, pp.44-52
Publisher: Elsevier Ltd
DOI: 10.1016/j.jcpa.2022.07.005
ISSN: 1532-3129
Organisation Unit: University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering
Language: English
Record Identifier: 99668498802621
Output Type: Journal article

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Collaboration types: Domestic collaboration
Web Of Science research areas: Pathology; Veterinary Sciences

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