Journal article
Pulmonary Histopathology in Cats and Dogs with Fatal Tick Paralysis
Journal of Comparative Pathology, Vol.197, pp.44-52
2022
PMID: 36089296
Abstract
The objective of this study was to evaluate critically the nature and prevalence of histological pulmonary lesions in dogs and cats that had died or were euthanized because of tick paralysis. A retrospective and prospective case study of 11 cats and 23 dogs was carried out. Retrospective cases were gathered from the Veterinary Laboratory Services database at The University of Queensland (UQ). Prospective cases were provided by Veterinary Specialist Services and UQ VETs Small Animal Hospital. Lung and other tissue samples were collected for histopathological analysis. All tick intoxicated animals demonstrated evidence of pulmonary parenchymal changes: alveolar oedema, interstitial and alveolar congestion and alveolar fibrin exudation. Eleven of 23 (48%) dogs exhibited mild to severe bronchopneumonia. A lower rate (18%) of bronchopneumonia was found in cats, with one case of aspiration pneumonia. A novel pulmonary histological grading scheme was developed to evaluate the correlation between clinical presentation and histopathological changes. Novel extrapulmonary lesions in cats included hepatic necrosis and acute renal tubular necrosis attributed to hypoxia. We concluded that both dogs and cats with high clinical grade tick paralysis are extremely likely to have pulmonary pathology. High-protein oedema and fibrin exudation are predicted to be present in most cases of canine and feline tick paralysis.
Details
- Title
- Pulmonary Histopathology in Cats and Dogs with Fatal Tick Paralysis
- Authors
- Yachen Wang (Author) - University of the Sunshine Coast, Queensland, School of Science, Technology and EngineeringNatalie Watters (Author) - The University of QueenslandEmily Jones (Corresponding Author) - The University of QueenslandAndrew Padula (Author) - The University of MelbourneEllie Leister (Author)Mark Haworth (Author) - The University of QueenslandJoerg Henning (Author) - The University of QueenslandRachel Allavena (Author) - The University of Queensland
- Publication details
- Journal of Comparative Pathology, Vol.197, pp.44-52
- Publisher
- Elsevier Ltd
- Date published
- 2022
- DOI
- 10.1016/j.jcpa.2022.07.005
- ISSN
- 1532-3129
- PMID
- 36089296
- Organisation Unit
- University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering
- Language
- English
- Record Identifier
- 99668498802621
- Output Type
- Journal article
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- Collaboration types
- Domestic collaboration
- Web Of Science research areas
- Pathology
- Veterinary Sciences
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