Journal article
Pseudoephedrine and preexercise feeding: Influence on performance
Medicine and Science in Sports and Exercise, Vol.45(6), pp.1152-1157
2013
PMID: 23274597
Abstract
Purpose: This study examined the influence of preexercise food intake on plasma pseudoephedrine (PSE) concentrations and subsequent high-intensity exercise. In addition, urinary PSE concentrations were measured under the same conditions and compared with the present threshold of the World Anti-Doping Agency (WADA). Methods: Ten highly trained male cyclists and triathletes (age = 30.6±6.6 yr, body mass [BM] = 72.9±5.1 kg, and VË™O2max = 64.8±4.5 mL.kg-1.min-1; mean±SD) undertook four cycling time trials (TT), each requiring the completion of a set amount of work (7 kJ.kg-1 BM) in the shortest possible time. Participants were randomized into a fed or nonfed condition and orally ingested 2.8 mg.kg-1 BM of PSE or a placebo (PLA) 90 min before exercise; in the fed trials, they consumed a meal providing 1.5 g.kg-1 BM of CHO. Venous blood was sampled at 30, 50, and 70 min and pre-warm-up and postexercise for the analysis of plasma PSE and catecholamine concentrations, and urine was also collected for the analysis of PSE concentration. Results: Independent of the preexercise meal, 2.8 mg.kg-1 BM of PSE did not significantly improve cycling TT performance. The fed trials resulted in lower plasma PSE concentrations at all time points compared with the nonfed trials. Both plasma epinephrine and blood lactate concentrations were higher in the PSE compared with the PLA trials, and preexercise and postexercise urinary PSE concentrations were significantly higher than the threshold (150 μg.mL-1) used by WADA to determine illicit PSE use. Conclusion: Irrespective of the preexercise meal, cycling TT performance of approximately 30 min was not improved after PSE supplementation. Furthermore, 2.8 mg.kg-1 BM of PSE taken 90 min before exercise, with or without food, resulted in urinary PSE concentrations exceeding the present WADA threshold.
Details
- Title
- Pseudoephedrine and preexercise feeding: Influence on performance
- Authors
- K R Pritchard-Peschek (Author) - University of QueenslandM A Osborne (Author) - Queensland Academy of SportGary J Slater (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and EngineeringD R Taaffee (Author) - University of QueenslandDavid G Jenkins (Author) - University of Queensland
- Publication details
- Medicine and Science in Sports and Exercise, Vol.45(6), pp.1152-1157
- Publisher
- Lippincott Williams & Wilkins
- Date published
- 2013
- DOI
- 10.1249/MSS.0b013e3182808e23
- ISSN
- 0195-9131
- PMID
- 23274597
- Organisation Unit
- University of the Sunshine Coast, Queensland; School of Health - Nutrition & Dietetics; School of Health and Sport Sciences - Legacy; School of Health and Behavioural Sciences - Legacy
- Language
- English
- Record Identifier
- 99449074202621
- Output Type
- Journal article
Metrics
6 File views/ downloads
585 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- Web Of Science research areas
- Sport Sciences
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites