Pseudoephedrine Ingestion and Cycling Time-Trial Performance

K R Pritchard-Peschek; David G Jenkins; M A Osborne; Gary J Slater

doi:10.1123/ijsnem.20.2.132

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Pseudoephedrine Ingestion and Cycling Time-Trial Performance

Journal article

Open access

Peer reviewed

Pseudoephedrine Ingestion and Cycling Time-Trial Performance

K R Pritchard-Peschek, David G Jenkins, M A Osborne and Gary J Slater

International Journal of Sport Nutrition and Exercise Metabolism, Vol.20(2), pp.132-138

2010

DOI: https://doi.org/10.1123/ijsnem.20.2.132

PMID: 20479486

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Abstract

sympathomimetic

supplementation

exercise

ergogenic aid

The aim of the current study was to investigate the effect of 180 mg of pseudoephedrine (PSE) on cycling time-trial (TT) performance. Six well-trained male cyclists and triathletes (age 33 ± 2 yr, mass 81 ± 8 kg, height 182.0 ± 6.7 cm, VO2max 56.8 ± 6.8 ml · kg–1 · min–1; M ± SD) underwent 2 performance trials in which they completed a 25-min variable-intensity (50–90% maximal aerobic power) warm-up, followed by a cycling TT in which they completed a fixed amount of work (7 kJ/kg body mass) in the shortest possible time. Sixty minutes before the start of exercise, they orally ingested 180 mg of PSE or a cornstarch placebo (PLA) in a randomized, crossover, double-blind manner. Venous blood was sampled immediately pre- and postexercise for the analysis of pH plus lactate, glucose, and norepinephrine (NE). PSE improved cycling TT performance by 5.1% (95% CI 0–10%) compared with PLA (28:58.9 ± 4:26.5 and 30:31.7 ± 4:36.7 min, respectively). There was a significant Treatment × Time interaction (p = .04) for NE, with NE increasing during the PSE trial only. Similarly, blood glucose also showed a trend (p = .06) for increased levels postexercise in the PSE trial. The ingestion of 180 mg of PSE 60 min before the onset of high-intensity exercise improved cycling TT performance in well-trained athletes. It is possible that changes in metabolism or an increase in central nervous system stimulation is responsible for the observed ergogenic effect of PSE.

Details

Title: Pseudoephedrine Ingestion and Cycling Time-Trial Performance
Authors: K R Pritchard-Peschek (Author) - University of Queensland
David G Jenkins (Author) - University of Queensland
M A Osborne (Author) - Queensland Academy of Sport
Gary J Slater (Author) - University of the Sunshine Coast - Faculty of Science, Health and Education
Publication details: International Journal of Sport Nutrition and Exercise Metabolism, Vol.20(2), pp.132-138
Publisher: Human Kinetics
Date published: 2010
DOI: 10.1123/ijsnem.20.2.132
ISSN: 1526-484X
PMID: 20479486
Organisation Unit: University of the Sunshine Coast, Queensland; School of Health - Nutrition & Dietetics; School of Health and Sport Sciences - Legacy; School of Health and Behavioural Sciences - Legacy
Language: English
Record Identifier: 99449214702621
Output Type: Journal article

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Collaboration types: Domestic collaboration
Web Of Science research areas: Nutrition & Dietetics; Sport Sciences

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