Prevalence of vascular complications and factors predictive of their development in young adults with type 1 diabetes: Systematic literature review

Steven James; R Gallagher; J Dunbabin; L Perry

doi:10.1186/1756-0500-7-593

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Prevalence of vascular complications and factors predictive of their development in young adults with type 1 diabetes: Systematic literature review

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Prevalence of vascular complications and factors predictive of their development in young adults with type 1 diabetes: Systematic literature review

Steven James, R Gallagher, J Dunbabin and L Perry

BMC Research Notes, Vol.7, pp.1-11

2014

DOI: https://doi.org/10.1186/1756-0500-7-593

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Abstract

quantitative epidemiological systematic review

vascular complications

prevalence

predictors

retinopathy

nephropathy

hypertension

young adults

type 1 diabetes

Background: Vascular complications curtail life expectancy and quality of life in type 1 diabetes and development at younger ages is particularly detrimental. To date no review has summarised the prevalence or factors predicting their development in young adults. Methods. A quantitative epidemiological systematic review was conducted to identify the prevalence and predictive factors for development of retinopathy, nephropathy and hypertension in young adults (sample age mean [plus 1SD] 18-30 years) with type 1 diabetes, using processes adapted from established review methods set out by the Centre for Reviews and Dissemination. MEDLINE (Ovid), Scopus (Elsevier), CINAHL, Science Direct (Elsevier), Google Scholar and Cochrane databases were searched to identify relevant articles published between 1993 and June 2014. From this eleven papers were retrieved, appraised and results summarised by three reviewers using established methods. Results: Some form of retinopathy occurred in up to almost half of participants; more severe forms affected up to one in ten. One in six was reported with microalbuminuria; one in 14 had macroalbuminuria. Hypertension occurred in almost one in two participants. Applying out-dated high thresholds this decreased to approximately one in ten participants. Glycaemic control was a consistent predictor of vascular disease in this age group. Conclusion: Prevalence rates of retinopathy, nephropathy and hypertension in young adults with type 1 diabetes emphasise the importance of regular complication screening for early detection and treatment. The predictive effect of glycaemic control reinforces its importance for prevention of vascular complications. © 2014 James et al.; licensee BioMed Central Ltd.

Details

Title: Prevalence of vascular complications and factors predictive of their development in young adults with type 1 diabetes: Systematic literature review
Authors: Steven James (Author) - The University of Sydney
R Gallagher (Author) - The University of Sydney
J Dunbabin (Author) - University of Newcastle Australia
L Perry (Author) - University of Technology Sydney
Publication details: BMC Research Notes, Vol.7, pp.1-11
Publisher: BioMed Central Ltd.
Date published: 2014
DOI: 10.1186/1756-0500-7-593
ISSN: 1756-0500
Copyright note: Copyright © 2014 James et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Organisation Unit: School of Health - Nursing; School of Nursing, Midwifery and Paramedicine - Legacy
Language: English
Record Identifier: 99451119502621
Output Type: Journal article

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