Journal article
Phosphine ligand-free RuCl3-catalyzed reductive N-alkylation of aryl nitro compounds
Tetrahedron, Vol.72(29), pp.4169-4176
2016
Abstract
Without using any additional ligands, RuCl3 efficiently catalyses the reductive N-alkylation of aryl nitro compounds with alcohols using bio-based glycerol as the hydrogen source and without the need for any added solvents. The reaction can be easily manipulated to produce either imines or secondary amines in high yields. RuCl3-catalyzed reductive N-alkylation of nitroarenes with alcohols affords the corresponding imine products in good to excellent yields. Under the same reaction conditions, the one-pot sequential reaction of nitroarenes with alcohols and glycerol also gives amines in higher yields.
Details
- Title
- Phosphine ligand-free RuCl3-catalyzed reductive N-alkylation of aryl nitro compounds
- Authors
- Da-Wei Tan (Author) - Soochow University, ChinaHong-Xi Li (Author) - Soochow University, ChinaDavid James Young (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and EngineeringJian-Ping Lang (Author) - Soochow University, China
- Publication details
- Tetrahedron, Vol.72(29), pp.4169-4176
- Publisher
- Pergamon
- Date published
- 2016
- DOI
- 10.1016/j.tet.2016.05.036
- ISSN
- 0040-4020
- Copyright note
- Copyright © 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
- Organisation Unit
- University of the Sunshine Coast, Queensland
- Language
- English
- Record Identifier
- 99450000202621
- Output Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web Of Science research areas
- Chemistry, Organic