Personality and the genetic risk for alcohol dependence

W S Slutske; A C Heath; P A F Madden; K K Bucholz; Dixie J Statham; N G Martin

doi:10.1037/0021-843X.111.1.124

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Personality and the genetic risk for alcohol dependence

Journal article

Peer reviewed

Personality and the genetic risk for alcohol dependence

W S Slutske, A C Heath, P A F Madden, K K Bucholz, Dixie J Statham and N G Martin

Journal of Abnormal Psychology, Vol.111(1), pp.124-133

2002

DOI: https://doi.org/10.1037/0021-843X.111.1.124

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Abstract

Psychology

personality

conduct disorder

genetic factors

twins

alcohol dependence

The extent to which the genetic risk for alcohol dependence (AD) and conduct disorder (CD) and their common genetic risk overlap with genetic factors contributing to variation in dimensions of personality was examined in a study of 6,453 individuals from 3,383 adult male and female same-sex and unlike-sex twin pairs from the Australian Twin Registry. The associations between the personality dimensions of positive emotionality, negative emotionality, and AD and CD risk were modest, whereas the associations between behavioral undercontrol and AD and CD risk were substantially higher. Genetic influences contributing to variation in behavioral undercontrol accounted for about 40% of the genetic variation in AD and CD risk and about 90% of the common genetic risk for AD and CD. These results suggest that genetic factors contributing to variation in dimensions of personality, particularly behavioral undercontrol, account for a substantial proportion of the genetic diathesis for AD and most of the common genetic diathesis for AD and CD among both men and women.

Details

Title: Personality and the genetic risk for alcohol dependence
Authors: W S Slutske (Author) - University of Missouri
A C Heath (Author) - Washington University
P A F Madden (Author) - Washington University
K K Bucholz (Author) - Washington University
Dixie J Statham (Author) - Queensland Institute of Medical Research
N G Martin (Author) - Queensland Institute of Medical Research
Publication details: Journal of Abnormal Psychology, Vol.111(1), pp.124-133
Publisher: American Psychological Association
Date published: 2002
DOI: 10.1037/0021-843X.111.1.124
ISSN: 0021-843X
Organisation Unit: School of Social Sciences - Legacy; University of the Sunshine Coast, Queensland
Language: English
Record Identifier: 99449742002621
Output Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Psychiatry; Psychology, Clinical; Psychology, Multidisciplinary

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