Peripheral nerve diffusion tensor imaging is reliable and reproducible

N G Simon; Jim Lagopoulos; T Gallagher; M Kliot; M C Kiernan

doi:10.1002/jmri.25056

Back

Peripheral nerve diffusion tensor imaging is reliable and reproducible

Journal article

Peer reviewed

Peripheral nerve diffusion tensor imaging is reliable and reproducible

N G Simon, Jim Lagopoulos, T Gallagher, M Kliot and M C Kiernan

Journal of Magnetic Resonance Imaging, Vol.43(4), pp.962-969

2016

DOI: https://doi.org/10.1002/jmri.25056

Files and links (1)

url

https://doi.org/10.1002/jmri.25056View

Published Version

Abstract

DTI

MRI

peripheral nerve

Purpose: To determine the reliability and reproducibility of peripheral nerve diffusion tensor imaging (DTI) in healthy subjects. Materials and Methods: We assessed the test-retest and interrater reliability studies of peripheral nerve DTI in a cohort of 12 healthy subjects (mean age 44.0 years, range 26-71 years). Magnetic resonance imaging (MRI) studies were performed on a 3T scanner (MR750, GE Healthcare). DTI and T1-weighted sequences were performed on the tibial and peroneal nerves in the knee. Each subject was scanned on three separate occasions. Image analyses were performed at two anatomic positions: the level of the lateral femoral condyle (position 1), and the superior pole of the patella (position 2). Analysis was performed using three software packages ("raters"): FuncTools, FSL, and Diffusion Toolkit. Metrics obtained included fractional anisotropy (FA), axial diffusivity (AD), and radial diffusivity (RD). Results: DTI metrics were not significantly different between each measurement position, except peroneal nerve AD and tibial nerve RD were higher at position 1 (P=0.02 and 0.04, respectively). There was no significant difference in DTI metrics between male and female subjects (P=0.10-0.99). The test-retest reliability of DTI metrics was high, maximal for FA (intraclass correlation coefficient [ICC]=0.96). ICC values for individual DTI metrics were similar between each measurement position, except that tibial nerve AD was significantly higher at position 2 (P=0.03). Interrater reliability was also high (ICC=0.95-0.96). Conclusion: We found peripheral nerve DTI to be reliable and reproducible, with few effects related to the postprocessing package used. © 2015 Wiley Periodicals, Inc.

Details

Title: Peripheral nerve diffusion tensor imaging is reliable and reproducible
Authors: N G Simon (Author) - University of Sydney
Jim Lagopoulos (Author) - University of Sydney
T Gallagher (Author) - Northwestern University Feinberg School of Medicine, United States
M Kliot (Author) - Northwestern University Feinberg School of Medicine, United States
M C Kiernan (Author) - University of Sydney
Publication details: Journal of Magnetic Resonance Imaging, Vol.43(4), pp.962-969
Publisher: John Wiley & Sons Inc.
Date published: 2016
DOI: 10.1002/jmri.25056
ISSN: 1053-1807
Organisation Unit: University of the Sunshine Coast, Queensland; Thompson Institute
Language: English
Record Identifier: 99449334502621
Output Type: Journal article

Metrics

4 File views/ downloads

854 Record Views

47 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Radiology, Nuclear Medicine & Medical Imaging

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: InCites