Pattern formation in the developing eye of Drosophila melanogaster is regulated by the homoeo-box gene, rough

R Saint; B Kalionis; T J Lockett; Abigail Elizur

doi:10.1038/334151a0

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Pattern formation in the developing eye of Drosophila melanogaster is regulated by the homoeo-box gene, rough

Journal article

Peer reviewed

Pattern formation in the developing eye of Drosophila melanogaster is regulated by the homoeo-box gene, rough

R Saint, B Kalionis, T J Lockett and Abigail Elizur

Nature, Vol.334, pp.151-154

1988

DOI: https://doi.org/10.1038/334151a0

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Abstract

Drosophila melanogaster

rough

eye development

Homoeo-box genes play a central role in the regulation of embryogenesis in Drosophila melanogaster. Their widespread phylogenetic distribution, and the tissue and stage specificity of their expression in other organisms, argue that they play a general and significant role in animal development. In D. melanogaster, all homoeo-box genes characterized to date are involved in major aspects of embryogenesis. We report here the molecular characterization of a Drosophila homoeo-box gene that has no apparent involvement in early embryogenesis. The gene appears to be rough, a gene implicated in pattern formation in the developing eye. It is expressed in cells within, and posterior to, the morphogenetic furrow, the site of the primary pattern forming events in the developing retina, and also in a region of the brain of the third instar larva. We have found no genetic or molecular evidence of a role for this gene in other aspects of fly development.

Details

Title: Pattern formation in the developing eye of Drosophila melanogaster is regulated by the homoeo-box gene, rough
Authors: R Saint (Author) - CSIRO Division of Entomology
B Kalionis (Author) - CSIRO Division of Entomology
T J Lockett (Author) - CSIRO Division of Biotechnology
Abigail Elizur (Author) - CSIRO Division of Entomology
Publication details: Nature, Vol.334, pp.151-154
Publisher: Nature Publishing Group
Date published: 1988
DOI: 10.1038/334151a0
ISSN: 0028-0836
Organisation Unit: University of the Sunshine Coast, Queensland; Centre for Bioinnovation
Language: English
Record Identifier: 99449822502621
Output Type: Journal article

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