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P300 event-related potentials in children with dyslexia
Journal article   Peer reviewed

P300 event-related potentials in children with dyslexia

E A Papagiannopoulou and Jim Lagopoulos
Annals of Dyslexia, Vol.67(1), pp.99-108
2017
url
https://doi.org/10.1007/s11881-016-0122-6View
Published Version

Abstract

auditory processing children dyslexia event-related potentials P300
To elucidate the timing and the nature of neural disturbances in dyslexia and to further understand the topographical distribution of these, we examined entire brain regions employing the non-invasive auditory oddball P300 paradigm in children with dyslexia and neurotypical controls. Our findings revealed abnormalities for the dyslexia group in (i) P300 latency, globally, but greatest in frontal brain regions and (ii) decreased P300 amplitude confined to the central brain regions (Fig. 1). These findings reflect abnormalities associated with a diminished capacity to process mental workload as well as delayed processing of this information in children with dyslexia. Furthermore, the topographical distribution of these findings suggests a distinct spatial distribution for the observed P300 abnormalities. This information may be useful in future therapeutic or brain stimulation intervention trials. © 2016 The International Dyslexia Association

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