Journal article
Outpatient Cognitive Behavioural Therapy Programme for Alcohol Dependence: Impact of Naltrexone Use on Outcome
Australian and New Zealand Journal of Psychiatry, Vol.35(4), pp.443-448
2001
PMID: 11531723
Abstract
Objective: Cognitive–behavioural therapy (CBT) has been effectively used in the treatment of alcohol dependence. Clinical studies report that the anticraving drug naltrexone, is a useful adjunct to treatment. Currently, few data are available on the impact of adding this medication to programmes in more typical, outpatient, and rehabilitation settings. The objective of this study was to examine the impact on outcome of adding naltrexone to an established outpatient alcohol rehabilitation program which employed CBT. Method: Fifty patients participated in an established 12-week, outpatient, ‘contract’-based alcohol abstinence programme which employed CBT. They also received naltrexone 50 mg orally daily (CBT + naltrexone). Outcomes were compared with 50 historical, matched controls, all of whom participated in the same programme without an anticraving medication (CBT alone). All patients met DSM-IV criteria for alcohol dependence. Results: Programme attendance across the eight treatment sessions was lower in the CBT alone group (p < 0.001). Relapse to alcohol use occurred sooner and more frequently in the CBT alone group (p < 0.001). Rehabilitation programme completion at 12 weeks was 88% (CBT + naltrexone) compared with 36% for (CBT alone) (p < 0.001). Alcohol abstinence at 12 weeks was 76% (CBT + naltrexone) compared with 18% (CBT alone) (p < 0.001). Conclusion: When employing the same outpatient rehabilitation programme and comparing outcomes using matched historical controls, the addition of naltrexone substantially improves programme attendance, programme completion and reported alcohol abstinence. In a typical outpatient programme, naltrexone addition was associated with significantly improved programme participation, better outcomes and was well tolerated.
Details
- Title
- Outpatient Cognitive Behavioural Therapy Programme for Alcohol Dependence: Impact of Naltrexone Use on Outcome
- Authors
- Gerald F.X Feeney (Author) - Princess Alexandra HospitalRoss Young (Author) - Princess Alexandra HospitalJason P Connor (Author) - Princess Alexandra HospitalJane Tucker (Author) - Princess Alexandra HospitalAnnie Mcpherson (Author) - Princess Alexandra Hospital
- Publication details
- Australian and New Zealand Journal of Psychiatry, Vol.35(4), pp.443-448
- Publisher
- Sage Publications Ltd.
- DOI
- 10.1046/j.1440-1614.2001.00935.x
- ISSN
- 1440-1614
- PMID
- 11531723
- Organisation Unit
- University of the Sunshine Coast, Queensland; Office of the Deputy Vice-Chancellor (Research and Innovation)
- Language
- English
- Record Identifier
- 99550991802621
- Output Type
- Journal article
Metrics
18 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- Web Of Science research areas
- Psychiatry
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites