Novel Mitochondrial Gene Content and Gene Arrangement Indicate Illegitimate Inter-mtDNA Recombination in the Chigger Mite, Leptotrombidium pallidum

Renfu Shao; H Mitani; S C Barker; M Takahashi; M Fukunaga

doi:10.1007/s00239-004-0226-1

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Novel Mitochondrial Gene Content and Gene Arrangement Indicate Illegitimate Inter-mtDNA Recombination in the Chigger Mite, Leptotrombidium pallidum

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Novel Mitochondrial Gene Content and Gene Arrangement Indicate Illegitimate Inter-mtDNA Recombination in the Chigger Mite, Leptotrombidium pallidum

Renfu Shao, H Mitani, S C Barker, M Takahashi and M Fukunaga

Journal of Molecular Evolution, Vol.60(6), pp.764-773

2005

DOI: https://doi.org/10.1007/s00239-004-0226-1

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Abstract

Biochemistry and Cell Biology

Evolutionary Biology

Genetics

Acari

double-strand break

end-joining repair

gene order

gene rearrangement

illegitimate recombination

mitochondrial genome

tRNA secondary structure

To better understand the evolution of mitochondrial (mt) genomes in the Acari (mites and ticks), we sequenced the mt genome of the chigger mite, Leptotrombidium pallidum (Arthropoda: Acari: Acariformes). This genome is highly rearranged relative to that of the hypothetical ancestor of the arthropods and the other species of Acari studied. The mt genome of L. pallidum has two genes for large subunit rRNA, a pseudogene for small subunit rRNA, and four nearly identical large noncoding regions. Nineteen of the 22 tRNAs encoded by this genome apparently lack either a T-arm or a D-arm. Further, the mt genome of L. pallidum has two distantly separated sections with identical sequences but opposite orientations of transcription. This arrangement cannot be accounted for by homologous recombination or by previously known mechanisms of mt gene rearrangement. The most plausible explanation for the origin of this arrangement is illegitimate inter-mtDNA recombination, which has not been reported previously in animals. In light of the evidence from previous experiments on recombination in nuclear and mt genomes of animals, we propose a model of illegitimate inter-mtDNA recombination to account for the novel gene content and gene arrangement in the mt genome of L. pallidum.

Details

Title: Novel Mitochondrial Gene Content and Gene Arrangement Indicate Illegitimate Inter-mtDNA Recombination in the Chigger Mite, Leptotrombidium pallidum
Authors: Renfu Shao (Author) - University of Queensland
H Mitani (Author) - Fukuyama University, Japan
S C Barker (Author) - University of Queensland
M Takahashi (Author) - Kawagoe Sogo Senior High School, Japan
M Fukunaga (Author) - Fukuyama University, Japan
Publication details: Journal of Molecular Evolution, Vol.60(6), pp.764-773
Publisher: Springer New York LLC
Date published: 2005
DOI: 10.1007/s00239-004-0226-1
ISSN: 0022-2844
Organisation Unit: School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering; Centre for Bioinnovation
Language: English
Record Identifier: 99450001902621
Output Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Biochemistry & Molecular Biology; Evolutionary Biology; Genetics & Heredity

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