Neutrophil counts in leptospirosis patients infected with different serovars

Scott B Craig; T A Collet; Sarah Jane Wynwood; Lee D Smythe; S L Weier; David B McKay

Back

Neutrophil counts in leptospirosis patients infected with different serovars

Journal article

Peer reviewed

Neutrophil counts in leptospirosis patients infected with different serovars

Scott B Craig, T A Collet, Sarah Jane Wynwood, Lee D Smythe, S L Weier and David B McKay

Tropical Biomedicine, Vol.30(4), pp.579-583

2013

Files and links (1)

url

http://www.msptm.org/files/579_-_583_Craig_SB.pdfView

Webpage

Abstract

neutrophil counts

leptospirosis patients

Queensland Health

In leptospirosis patients, haematological abnormalities have been reported. The aim of this study was to determine if neutrophil counts were different between patients known to be infected with a range of leptospiral serovars. The study retrospectively compared the neutrophil counts from the first blood samples taken from 210 leptospirosis patients at first presentation to a Queensland Health hospital. Significant differences (p less than 0.001) were observed in neutrophil counts across the 11 different infecting serovars. These findings suggest that neutrophil counts may be useful in the development of an algorithm determining the infecting serovar in suspected leptospirosis patients. Further studies are required to delineate host cytokine responses which may suggest the underlying aetiology of the observed differences in neutrophil counts. Such studies would also provide valuable therapeutic insights into treating the disease.

Details

Title: Neutrophil counts in leptospirosis patients infected with different serovars
Authors: Scott B Craig (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and Engineering
T A Collet (Author) - Queensland University of Technology
Sarah Jane Wynwood (Author) - WHO/OIE/FAO Collaborating Centre for Reference and Research on Leptospirosis
Lee D Smythe (Author) - WHO/OIE/FAO Collaborating Centre for Reference and Research on Leptospirosis
S L Weier (Author) - Queensland University of Technology
David B McKay (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and Engineering
Publication details: Tropical Biomedicine, Vol.30(4), pp.579-583
Publisher: Malaysian Society of Parasitology and Tropical Medicine
Date published: 2013
ISSN: 0127-5720
Organisation Unit: School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering
Language: English
Record Identifier: 99448796302621
Output Type: Journal article

Metrics

2 File views/ downloads

893 Record Views