Neonatal cardiac MRI using prolonged balanced SSFP imaging at 3T with active frequency stabilization

A N Price; S J Malik; Kathryn Broadhouse; A E Finnemore; G Durighel; D J Cox; A D Edwards; A M Groves; J V Hajnal

doi:10.1002/mrm.24518

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Neonatal cardiac MRI using prolonged balanced SSFP imaging at 3T with active frequency stabilization

Journal article

Peer reviewed

Neonatal cardiac MRI using prolonged balanced SSFP imaging at 3T with active frequency stabilization

A N Price, S J Malik, Kathryn Broadhouse, A E Finnemore, G Durighel, D J Cox, A D Edwards, A M Groves and J V Hajnal

Magnetic Resonance in Medicine, Vol.70(3), pp.776-784

2013

DOI: https://doi.org/10.1002/mrm.24518

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Abstract

balanced SSFP

neonatal cardiac MRI

frequency drift

B0 shimming

Cardiac MRI in neonates holds promise as a tool that can provide detailed functional information in this vulnerable group. However, their small size, rapid heart rate, and inability to breath-hold, pose particular challenges that require prolonged high-contrast and high-SNR methods. Balanced-steady state free precession (SSFP) offers high SNR efficiency and excellent contrast, but is vulnerable to off-resonance effects that cause banding artifacts. This is particularly problematic in the blood-pool, where off-resonance flow artifacts severely degrade image quality. Methods: In this article, we explore active frequency stabilization, combined with image-based shimming, to achieve prolonged SSFP imaging free of banding artifacts. The method was tested using 2D multislice SSFP cine acquisitions on 18 preterm infants, and the functional measures derived were validated against phase-contrast flow assessment. Results: Significant drifts in the resonant frequency (165±23Hz) were observed during 10-min SSFP examinations. However, full short-axis stacks free of banding artifacts were achieved in 16 subjects with stabilization; the cardiac output obtained revealed a mean difference of 9.0±8.5% compared to phase-contrast flow measurements. Conclusion: Active frequency stabilization has enabled the use of prolonged SSFP acquisitions for neonatal cardiac imaging at 3T. The findings presented could have broader implications for other applications using prolong SSFP acquisitions.

Details

Title: Neonatal cardiac MRI using prolonged balanced SSFP imaging at 3T with active frequency stabilization
Authors: A N Price (Author) - Imperial College London, United Kingdom
S J Malik (Author) - Imperial College London, United Kingdom
Kathryn Broadhouse (Author) - Imperial College London, United Kingdom
A E Finnemore (Author) - Imperial College London, United Kingdom
G Durighel (Author) - Imperial College London, United Kingdom
D J Cox (Author) - Imperial College London, United Kingdom
A D Edwards (Author) - Imperial College London, United Kingdom
A M Groves (Author) - Imperial College London, United Kingdom
J V Hajnal (Author) - Imperial College London, United Kingdom
Publication details: Magnetic Resonance in Medicine, Vol.70(3), pp.776-784
Publisher: John Wiley & Sons Inc.
Date published: 2013
DOI: 10.1002/mrm.24518
ISSN: 0740-3194; 0740-3194
Organisation Unit: School of Science and Engineering - Legacy; School of Health - Nursing; University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy
Language: English
Record Identifier: 99451501102621
Output Type: Journal article

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Collaboration types: Domestic collaboration
Web Of Science research areas: Radiology, Nuclear Medicine & Medical Imaging

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